Zallouh sexual product
Root zallouh, ferula hermonis

Zallouh is made from the dried root of the herb Ferula Hermonis which grows at a height of about 2000 meters above sea level on the side of Mount Hermoun between Lebanon and Syria. Zallouh has been used historically in the region as an aphrodisiac, but it has only been in the past few years that scientists have evaluated it's chemical properties. Zallouh contains a number of compounds, including sesquiterpenes. For more Zallouh information.

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Zallouh Research
An intriguing study in male rats showed that zallouh, when given one time, enhanced sexual activity, and also raised blood levels of testosterone. However, when zallouh was given daily for 10 days, it actually reduced sexual activity, and also reduced testosterone levels.

The crude oil from zallouh can enhance erectile function in rodents, however zallouh becomes toxic if used for a long period of time in high doses. For information on impotence.

In mice, the ingestion of 3 mg/kg of aqueous extract of zallouh for six weeks inhibited social aggression. Body weight and other sex accessory organ weights were significantly reduced. The ingestion of high doses of zallouh by male mice resulted in a significant reduction of their fertility.

Summary
At this point it is difficult to make any firm recommendations regarding the use of zallouh. Occasional use appears to be safe, but long term use is discouraged until more is known whether or not zallouh is toxic with chronic use.

Ferutinin stimulates nitric oxide synthase activity in median eminence of the rat.
J Ethnopharmacol. 2006 Jul 19;106(3):327-32. Laboratory of Bioassays and Natural Products, Laboratory of Molecular Modeling, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.
Several species of Ferula genus have been used in folk medicine in digestive disorders, rheumatism, headache, arthritis, and as tranquilizers, antispasmodic and aphrodisiac. From the dry and powdered roots of Ferula hermonis Boiss was extracted the oxygenated sesquiterpene 1,5-trans-daucane type: ferutinine. The possible signaling pathway of ferutinin in nervous tissue in vitro was assessed and the results showed that this compound is able to increase nitric oxide synthase activity and inositol monophosphate accumulation in the median eminence of the rat brain, suggesting that compound is associated to the activation of phosphoinositide breakdown and nitric oxide production, the last is a gaseous intercellular messenger known to play a broad role in human biology from homeostasis to pathology.

Zallouh Research Update
Opposite effect of acute and subchronic treatments with Ferula hermonis on copulatory behavior of male rats.
Zanoli P, Benelli A. University of Modena and Reggio Emilia, Modena, Italy.
Int J Impot Res. 2003 Dec;15(6):450-5.
Sexually potent and sluggish/impotent male rats were orally treated with an extract of Ferula hermonis (30 and 60 mg/kg). The acute administration stimulated sexual motivation in potent rats and improved copulatory performance in sluggish/impotent rats. This last effect was elicited only by the higher dose, which, in parallel, increased serum testosterone levels in rats. On the contrary, when the extract was subchronically administered (10 days) a marked reduction in the percentage of rats achieving ejaculation was detected, together with a general impairment of the copulatory pattern. Furthermore, the repeated administration of the extract (6 mg/kg/day for 10 days) resulted in a significant reduction of testosterone levels in comparison with controls. The present results discourage a repeated assumption of zallouh, while suggesting its acute administration to improve the performance in sexual dysfunctions.

A comparative study of Ferula hermonis root extracts (zallouh) and sildenafil on copulatory behaviour of male rats.
Hadidi KA,. Faculty of Medicine, University of Jordan, Amman 11942, Jordan.
Fitoterapia. 2003 Apr;74(3):242-6.
The effect of 600 mg/kg given by oral route to rats of Ferula hermonis (zallouh) roots extracts (petroleum ether, ethyl acetate, methanol and water) was evaluated on sexual behaviour of male rats. Petroleum ether and ethyl acetate extracts of zallouh produced a significant decrease in both the mount rate (MR) and the intromission rate (IR), significant prolongation of intromission latency (IL) was observed when these extracts were compared with both controls and sildenafil. Methanolic extract produced a significant increase in MR while no effect has been observed on IR or IL in comparison with control. The effect of zallouh water extract was not significantly different from controls for the MR and IR, but there was a significant prolongation in the IL

Zallouh questions
Q. Can zallouh be effective for erectile dysfunction? Can you also tell me about suma as sexual enhancer?
   A. We have not seen enough research yet in humans, but it is possible. Passion Rx is quite helpful for erectile dysfunction. See suma research here.

root zallouh, ferula, zallouh libido, zallouh information

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