Yohimbe is the name of the bark of a tall evergreen tree in western Africa known as Pausinystalia yohimbe or Corynanthe yohimbe. Yohimbe has been used for centuries in some western African nations for the treatment of erectile dysfunction.
      Yohimbe bark has been reported to contain up to 6% total alkaloids, 10-15% of which is yohimbine. Yohimbine is a drug approved by the FDA for the treatment of erectile dysfunction. Almost all clinical studies have been conducted with yohimbine rather than yohimbe bark. For more than 80 years yohimbine has been used as a treatment for male and female sexual difficulties. Yohimbe is often thought of as a therapy for erectile dysfunction in men. Most people don't realize that yohimbe is also effective in women. Women like the enhanced sensation and engorgement of genital organs that yohimbe provides. Also consider a product that works really well in sexual enhancement, it is called Passion Rx. Another herb that works well is tongkat ali.

Yohimbe Bark Natrol
Whole Herb Yohimbe Powder Dietary Supplement

Yohimbe Supplement Facts:
Yohimbe bark - 500 mg

Click here to buy Yohimbe herb product

Directions: Take half a yohimbe pill an hour or two before activity. If you are sensitive to herbs, take less than half. Yohimbe is not recommended for anyone with heart problems or who has heart irregularities. Note: some people with clinical impotence or erectile dysfunction may have underlying heart disease. Be cautious using herbs or drugs for sexual enhancement until a thorough medical evaluation has been done. Another option is Passion Rx with Yohimbe which works very well with fewer side effects.

*Yohimbe daily value not established.
Warning: If you are under medical supervision for any condition, consult your healthcare professional before using yohimbe or any yohimbe extract.

What the Research Says about Yohimbe extract
Yohimbine has been evaluated in the management of erectile disorder by means of many placebo-controlled trials. It does appear to have a modest therapeutic benefit, particularly in psychological cases of erectile disorder. Here's one summary of a study: In contract, yohimbe extract has not been studied much.
   A 1977 German double-blind, placebo-controlled clinical trial of yohimbine hydrochloride included 86 patients with erectile dysfunction and without clearly detectable organic or psychologic causes. Yohimbine was administered orally in a dosage of 30 mg a day (two 5 mg tablets three times daily) for eight weeks. Patients were seen for follow-up after four weeks' treatment, and for a final visit after eight weeks. Efficacy evaluation was based on both subjective and objective criteria. Subjective criteria included improvement in sexual desire, sexual satisfaction, frequency of sexual contacts, and quality of erection (penile rigidity) during sexual contact/intercourse. Objective criteria of outcome were based on improvement in penile rigidity determined by use of polysomnography in the sleep laboratory. Overall Yohimbine was found significantly more effective than placebo in terms of response rate: 71 vs 45%. Yohimbine was well-tolerated: Only 7% of patients rated tolerability fair or poor, and most adverse experiences were mild. There was no serious adverse event.

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Women and Yohimbe extract
A study conducted at the University of Texas at Austin, Texas examined the effects of Arginine combined with yohimbine on sexual arousal in postmenopausal women with Female Sexual Arousal Disorder. Twenty-four women participated in three treatment sessions in which self-report and vaginal sexual responses to erotic stimuli were measured following treatment with either L-arginine (6 g) plus yohimbine (6 mg), yohimbine alone (6 mg), or placebo, using a randomized, double-blind, three-way cross-over design. Sexual responses were measured at approximately 60 minutes postdrug administration. The combined oral administration of L-arginine and yohimbine substantially increased vaginal pulse amplitude responses to the erotic film at 60 min postdrug administration compared with placebo. The vaginal response was measured with an instrument called a vaginal photoplethysmograph.

Yohimbe extract mechanism of Action
Yohimbine acts through the nervous system to increase blood flow to the genital region. Although many pharmacological properties of yohimbine have been described, at the plasma concentration attained at recommended dosages in humans the predominant activity is antagonism of alpha 2-adrenoceptors. Erectile dysfunction improvement can occur with certain natural herbs such as yohimbe extract.

Yohimbe extract side effects
Yohimbe should be used cautiously by anyone with a medical condition, particularly those with hypertension, heart disease, diabetes, or those taking medicines, particularly tranquilizers, antidepressants, sedatives, antihistamines, amphetamines or other stimulants, including caffeine. Yohimbine induces noradrenaline secretion. Some of the side effects of yohimbe include anxiety, changes in blood pressure, heart rate increase or palpitations, dizziness, headache, visual disturbances, nausea or abdominal cramps, increased body temperature and sweating.
   Since high doses of yohimbe may cause confusion and disorientation, it should not be taken while operating machinery, driving, or performing hazardous activities.

Availability of Yohimbe bark extract
Yohimbe bark is sold widely in different dosages and extract potencies including 4%, 6%, 8%, and 10% alkaloids. It is difficult to give precise dosage recommendations for yohimbe extracts since sometimes manufacturers and formulas are not consistent in their content or extract potencies of yohimbe. In one study, of twenty commercial aphrodisiac preparations were analysed and the amount of yohimbine measured and expressed as the maximal dose per day suggested on product labels ranged from 1.32 to 23.16 mg.

Timing and Frequency of Yohimbe extract use
Yohimbe bark extract may be used either daily or before planned activity. In my opinion, since yohimbe works quite quickly, it makes sense that it be taken as needed one to three hours before planned sexual activity rather than taken daily. The effects last several hours. I don't recommend you take yohimbe extract close to bedtime since it can have a stimulant and alertness causing effect for several hours.

Yohimbe extract Research Update
Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats.
Ajayi AA, Newaz M. Texas Southern University, Houston 77004, USA
Methods Find Exp Clin Pharmacol. 2003 Dec;25(10):817-22.
The bark of the African tree Yohimbe has been used as a food additive with aphrodisiac and penile erection enhancing properties. The effect of an aqueous extract of yohimbe on renal circulation was assessed in order to test the hypothesis that it possesses additional effects on nitric oxide production and/or endothelin-1 (ET-1)-like actions. In vivo studies with yohimbe in Sprague Dawley rats demonstrated a dose-dependent (1-1000 ng/kg) increase in mean blood pressure and an increase in medullary blood flow (MBF). Both the pressor action and renal medullary vasodilation were blocked by endothelinA (ETA) receptor antagonist BMS182874 and endothelinB (ETB) receptor antagonist BQ788 in combination. L-Nomega-nitro-l-arginine methyl ester (L-NAME; 10 mg/kg) also inhibited the increase in MBF induced by yohimbe. In vitro studies in isolated perfused kidney and in pressurized renal microvessels confirmed the dose-dependent vasoconstrictor action of this extract. ETA receptor antagonist BQ610 and ETB receptor antagonist BQ788 separately and significantly attenuated the renal vasoconstrictor actions of the yohimbe extract. These preliminary observations indicate that, in addition to the alpha-adrenergic antagonist actions that characterize yohimbine, yohimbe possesses endothelin-like actions and affects nitric oxide (NO) production in renal circulation. These findings suggest a strong possibility of post-receptor cross-talk between alpha2-adrenoceptors and endothelin, as well as a direct effect of alpha2-adrenoceptors on renal NO production. yohimbe research, yohimbe nitric oxide, yohimbe endothelin.

Yohimbe Emails
Q. What's the most common side effect from yohimbe extract?
   A. The first thing you may notice after an hour or two of taking a yohimbe extract capsule or tablet is sweating under the arms. On higher doses of yohimbe bark you will notice a higher body temperature, an even higher doses of yohimbe lead to slightly blurred vision, mild anxiety, and a sense of not feeling well. Very high doses of yohimbe lead to heart palpitations. Fortunately, most of these yohimbe side effects only last an hour or two.

Q. I'm on beta blockers, can I take yohimbe bark extract?
   A. Beta blockers are known to lower sex drive and cause erectile dysfunction. Small amounts of yohimbe taken infrequently should not cause any problems, but of course this has to be done under medical supervision.

Q. Can I take yohimbe extract if I have high blood pressure?
   A. It depends. If you have moderate to severe hypertension, then you should avoid yohimbe. However, if you have mild hypertension, then small amounts of yohimbe, that is, less than 150 mg, should be fine, especially with the consent of your doctor. The blood pressure effects of yohimbe don't last all day, only a few hours.

Q. Can yohimbe extract be taken regularly for many months?
   A. As with most herbs, we recommend taking breaks from use. In the case of yohimbe bark extract, it's best to take it as needed since it works so quickly and there's no need for it to build up in the system like other herbs. Plus, the side effects of long term use of yohimbe on a daily basis in humans is not known.

Q. Is it okay to workout after taking a yohimbe product?
   A. Yohimbe increases body temperature, so we don't think it's a good idea to take it and engage in heavy physical activity, particularly in warm weather. Avoid yohimbe if you plan to be exposed to very hot temperatures. Drink cold water if you take a yohimbe product.

Q.  I tried Yohimbe bark extract for daytime sleepiness. It worked, but not as well as I would like. However 5 hours later my blood pressure was 174/101. I checked it twice. This is unacceptable. End of experiment. Pure Yohimbine HCl does not do anything for daytime sleepiness; however yohimbe bark does work. I have noticed before that yohimbe bark works. Conclusion: Something in yohimbe bark besides yohimbine is having the desired effect. Some separational chemistry is in order to find what that substance is and separate it from yohimbine. In the literature I note that some people get good results for narcolepsy with 4 to 6 mg of yohimbine. But not all narcolepsy is the same. When I was younger a neurologist put me on d-amphetamine. No matter how much of it I took, I could fall asleep on it. If the dose was high enough, all I got out of it was a headache. End of that route. I have not tried anything since until yohimbe. Also with age the narcolepsy moderated so it was no longer a major concern.

Q. Is yohimbe the best erectile dysfunction herb?
   A. Yohimbe is a very quick-acting erectile dysfunction herb, but due to its side effects, we don't think it is the best.

Q. Is it okay to take a low dose yohimbe supplement along with suma herb?
   A. For more suma information. Yes, it should be fine as long as the dosages are low.

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