Yohimbe is the name of the bark of a tall evergreen tree
in western Africa known as Pausinystalia yohimbe or Corynanthe yohimbe.
Yohimbe has been used for centuries in some western African nations for the
treatment of erectile
dysfunction.
Yohimbe bark has been reported to contain up to 6% total alkaloids, 10-15% of which is
yohimbine. Yohimbine is a drug approved by the FDA for the treatment of erectile
dysfunction. Almost all clinical studies have been conducted with yohimbine rather than
yohimbe bark. For more than 80 years yohimbine has been used as a treatment for male and
female sexual difficulties. Yohimbe is often thought of as a therapy for erectile
dysfunction in men. Most people don't realize that yohimbe is also effective in
women. Women like the enhanced sensation and engorgement of genital organs that yohimbe
provides. Also consider a product that works really well in sexual enhancement,
it is called Passion Rx.
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Whole
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Yohimbe Supplement Facts:
Yohimbe bark - 500 mg
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Directions: Take half a yohimbe pill an hour or two before activity. If you
are sensitive to herbs, take less than half. Yohimbe is not recommended for
anyone with heart problems or who has heart irregularities. Note: some people
with clinical impotence or erectile dysfunction may have underlying heart
disease. Be cautious using herbs or drugs
for sexual enhancement until a thorough medical evaluation has been done.
Another option is Passion Rx with Yohimbe which works very well with fewer side
effects.
*Yohimbe daily value not established.
Warning: If you are under medical supervision for any condition, consult your
healthcare professional before using yohimbe or any yohimbe extract.
Passion Rx with Yohimbe extract
Highly
touted sexual pleasure pills for Men and Women with low doses of Yohimbe
extract.
Women and Yohimbe extract
A study conducted at the University of Texas at Austin, Texas examined the
effects of arginine
combined with yohimbine on sexual arousal in postmenopausal
women with Female Sexual Arousal Disorder. Twenty-four women participated in
three treatment sessions in which self-report and vaginal sexual responses to
erotic stimuli were measured following treatment with either L-arginine (6 g)
plus yohimbine (6 mg), yohimbine alone (6 mg), or placebo, using a randomized,
double-blind, three-way cross-over design. Sexual responses were measured at
approximately 60 minutes postdrug administration. The combined oral
administration of L-arginine and yohimbine substantially increased vaginal pulse
amplitude responses to the erotic film at 60 min postdrug administration
compared with placebo. The vaginal response was measured with an instrument
called a vaginal photoplethysmograph.
Yohimbe extract mechanism of Action
Yohimbine acts through the nervous system to increase blood flow to the
genital region. Although many pharmacological properties of yohimbine have been described,
at the plasma concentration attained at recommended dosages in humans the predominant
activity is antagonism of alpha 2-adrenoceptors.
Erectile dysfunction improvement can occur with certain natural herbs such
as yohimbe extract.
Yohimbe extract side effects
Yohimbe should be used cautiously by anyone with a medical condition,
particularly those with hypertension, heart disease, diabetes, or those taking medicines,
particularly tranquilizers, antidepressants, sedatives, antihistamines, amphetamines or
other stimulants, including caffeine. Yohimbine induces noradrenaline secretion. Some of
the side effects of yohimbe include anxiety, changes in blood pressure, heart rate
increase or palpitations, dizziness, headache, visual disturbances, nausea or abdominal
cramps, increased body temperature and sweating.
Since high doses of yohimbe may cause confusion
and disorientation, it should not be taken while operating machinery, driving, or
performing hazardous activities.
Availability of Yohimbe bark extract
Yohimbe bark is sold widely in different dosages and extract potencies including 4%,
6%, 8%, and 10% alkaloids. It is difficult to give precise dosage
recommendations for yohimbe extracts since sometimes manufacturers and formulas
are not consistent in their content or extract potencies of yohimbe. In one
study, of
twenty commercial aphrodisiac preparations were analysed and
the amount of yohimbine measured and expressed as the maximal dose per day
suggested on product labels ranged from 1.32 to 23.16 mg.
Timing and Frequency of Yohimbe extract use
Yohimbe bark extract may be used either daily or before planned activity. In my opinion,
since yohimbe works quite quickly, it makes sense that it be taken as needed one
to three hours before planned sexual activity rather than taken daily. The
effects last several hours. I don't recommend you take yohimbe extract close to bedtime
since it can have a stimulant and alertness causing effect for several hours.
Yohimbe extract Research Update
Endothelin-like action of Pausinystalia yohimbe aqueous extract on
vascular and renal regional hemodynamics in Sprague Dawley rats.
Ajayi AA, Newaz M. Texas Southern University, Houston 77004, USA
Methods Find Exp Clin Pharmacol. 2003 Dec;25(10):817-22.
The bark of the African tree Yohimbe has been used as a food
additive with aphrodisiac and penile erection enhancing properties. The effect
of an aqueous extract of yohimbe on renal circulation was assessed in
order to test the hypothesis that it possesses additional effects on nitric
oxide production and/or endothelin-1 (ET-1)-like actions. In vivo studies with yohimbe in Sprague Dawley rats demonstrated a dose-dependent (1-1000 ng/kg)
increase in mean blood pressure and an increase in medullary blood
flow (MBF). Both the pressor action and renal medullary vasodilation
were blocked by endothelinA (ETA) receptor antagonist BMS182874 and endothelinB
(ETB) receptor antagonist BQ788 in combination. L-Nomega-nitro-l-arginine methyl
ester also inhibited the increase in MBF induced by yohimbe. In
vitro studies in isolated perfused kidney and in pressurized renal microvessels
confirmed the dose-dependent vasoconstrictor action of this extract. ETA
receptor antagonist BQ610 and ETB receptor antagonist BQ788 separately and
significantly attenuated the renal vasoconstrictor actions of the yohimbe extract. These preliminary observations indicate that, in addition to the
alpha-adrenergic antagonist actions that characterize yohimbine, yohimbe possesses endothelin-like actions and affects nitric oxide NO production in renal
circulation. These findings suggest a strong possibility of post-receptor
cross-talk between alpha2-adrenoceptors and endothelin, as well as a direct
effect of alpha2-adrenoceptors on renal NO production. Yohimbe
nitric oxide and endothelin production.
Yohimbe pill emails
Q. What's the most common side effect from
yohimbe extract?
A. The first thing you may notice after an hour or two of taking a yohimbe
extract capsule or tablet is sweating under the arms. On higher doses of yohimbe
bark
you will notice a higher body temperature, an even higher doses of yohimbe lead
to slightly blurred vision, mild anxiety, and a sense of not feeling well. Very
high doses of yohimbe lead to heart palpitations. Fortunately, most of these
yohimbe side effects only last an hour or two.
Q. I'm on beta blockers, can I take yohimbe bark extract? What about
tribulus terrestris extract?
A. Beta blockers are known to lower sex drive and cause erectile dysfunction.
Small amounts of yohimbe taken infrequently should not cause any problems, but
of course this has to be done under medical supervision. Tribulus herb is
another option.
Q. Can I take yohimbe extract if I have high blood pressure?
A. It depends. If you have moderate to severe hypertension, then you should
avoid yohimbe. However, if you have mild hypertension, then small amounts of
yohimbe, that is, less than 150 mg, should be fine, especially with the consent
of your doctor. The blood pressure effects of yohimbe don't last all day, only a
few hours.
Q. Can yohimbe extract be taken regularly for many months?
A. As with most herbs, we recommend taking breaks from use. In the case of yohimbe
bark extract, it's best to take it as needed since it works so
quickly and there's no need for it to build up in the system like other herbs.
Plus, the side effects of long term use of yohimbe on a daily basis in humans is
not known.
Q. Is it okay to workout after taking a yohimbe product?
A. Yohimbe increases body temperature, so we don't think it's a good idea to take
it and engage in heavy physical activity, particularly in warm weather. Avoid yohimbe if you plan to be exposed to very hot temperatures. Drink cold
water if you take a yohimbe product.
Q. I tried Yohimbe bark extract for daytime sleepiness. It worked, but not as well as I would like. However 5 hours later my blood pressure was 174/101. I checked it twice. This is unacceptable. End of experiment. Pure Yohimbine HCl does not do anything for daytime sleepiness; however yohimbe bark does work. I have noticed before that yohimbe bark works. Conclusion: Something in yohimbe bark besides yohimbine is having the desired effect. Some separational chemistry is in order to find what that substance is and separate it from yohimbine. In the literature I note that some people get good results for narcolepsy with 4 to 6 mg of yohimbine. But not all narcolepsy is the same. When I was younger a neurologist put me on d-amphetamine. No matter how much of it I took, I could fall asleep on it. If the dose was high enough, all I got out of it was a headache. End of that route. I have not tried anything since until yohimbe. Also with age the narcolepsy moderated so it was no longer a major concern.
Q. Is yohimbe the best erectile dysfunction herb?
A. Yohimbe is a very quick-acting
erectile dysfunction herb,
but due to its side effects, we don't think it is the best.
Q. Is it okay to take a low dose yohimbe supplement
along with suma herb?
A.
For more suma information.
Yes, it should be fine as long as the dosages are low.
Is yohimbe product to be taken ONLY when
contemplating sexual activity, or is it to be taken daily as a means to lessen
the effects of impotence ed, and to improve the performance of the system? How
long should one take yohimbe? If yohimbe pill is to be used to lessen the
effects of impotence ed, how far ahead of when one plans sexual activity should
one begin dosages of this product? Please note that yohimbe product was
recommended by my physician, and I have discussed its possible side effects, and
general usage with him thoroughly.
Most people take a yohimbe pill about 2 to 4 hours before sexual
activity. The effective dosage varies among individuals and it is a good idea to
begin with a low dosage in order to avoid side effects that can come from higher
dosages. There are sexual enhancement products that contain yohimbe which work
even better. One such product is Passion Rx with yohimbe which is taken in the
morning on an empty stomach 2 days in a row and then every other day or every
third day for maintenance. It may take trial and error to find out the best
yohimbe dosage that provides the most benefits with the least side effects.
I am inquiring as to whether you have any herb
that contains Yohimbine that would be used as a male sexual enhancer, if so,
could you send me whatever information you might have regarding this issue, or
maybe the best internet site I could log onto in order to purchase these herbs.