Tyrosine supplement - Health benefit of tyrosine
Tyrosine is not an essential amino acid since tyrosine can be
made from the amino acid phenylalanine. Tyrosine can be converted into
dopamine and norepinephrine. Supplementation with both tyrosine and phenylalanine leads to alertness
and arousal.
Phenylalanine and tyrosine are sometimes
prescribed as antidepressants, usually in combination with other nutrients and herbs that
have mood elevating properties. Some doctors also recommend these amino acids for appetite
control. Phenylalanine may trigger the release of an appetite-suppressing hormone in the
gut called cholecystokinin. Most individuals who take either of these amino acids notice
improved alertness, arousal, and mood, and slight loss in appetite. I have a few patients
who occasionally take a small amount of these nutrients, such as 50 to 250 mg, in the
morning as a substitute for caffeine. For more
tyrosine information.
Tyrosine 750 mg,
Club Natural
L Tyrosine Supplement Facts
L Tyrosine - 750 mg
If you plan to take tyrosine, limit your dose initially to a third or half a
capsule until you find out how tyrosine reacts in your system.
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Tyrosine supplements and cold
tolerance
Perhaps tyrosine raises body temperature, or just the fact that it converts to
certain catecholamines, may make it more useful to those who live in cold
climates.
Dietary tyrosine benefits cognitive and psychomotor
performance during body cooling.
Physiol Behav. 2007 Feb 28;90(2-3):301-7. O'Brien C, Mahoney C,
Tharion WJ, Sils IV, Castellani JW. Thermal and Mountain Medicine Division, U.S.
Army Research Institute of Environmental Medicine, Natick, MA 01760, USA.
Supplemental tyrosine is effective at limiting cold-induced decreases in working
memory, presumably by augmenting brain catecholamine levels, since tyrosine is a
precursor for catecholamine synthesis. The effectiveness of tyrosine for
preventing cold-induced decreases in physical performance has not been examined.
This study evaluated the effect of tyrosine supplementation on cognitive,
psychomotor, and physical performance following a cold water immersion protocol
that lowered body core temperature. Fifteen subjects completed a control trial
(CON) in warm (35 degrees C) water and two cold water trials, each spaced a week
apart. Subjects ingested an energy bar during each trial; on one cold trial (
tyrosine ) the bar contained tyrosine (300 mg/kg body weight), and on the other
cold trial ( placebo ) and on CON the bar contained no tyrosine... These
data support previous findings that dietary tyrosine supplementation is
effective for mitigating cold-induced cognitive performance such as working
memory, even with reduced core temperature, and extends those findings to
include the psychomotor task of marksmanship.
Tyrosine hydroxylase for depression
A novel therapeutic approach to depression via supplement with tyrosine
hydroxylase.
Biochem Biophys Res Commun. 2006 Dec 8;351(1):140-5. Institute of
Neurobiology, Fudan University, Shanghai 200433, China.
Tyrosine hydroxylase is the rate-limiting enzyme in the biosynthesis of
catecholamine neurotransmitters, dopamine, noradrenaline, and adrenaline, in the
neurons. The regulated activity of Tyrosine hydroxylase is thought to play a
critical role in modulating the functional activity of catecholaminergic
neuronal systems in the brain. It is well known that the catecholaminergic
neuronal systems are associated with depression. Here we showed that Tyrosine
hydroxylase, delivered by protein transduction domain, passed through the
blood-brain barrier and entered the neurons. Systemic Tyrosine hydroxylase
treatment improved the behavioral despair in the forced swim test and the tail
suspension test, the two models widely used to screen the potential
anti-depressant efficacy. The results indicated a novel and potential
therapeutic use of Tyrosine hydroxylase in the depression disorder.
Tyrosine Emails
Q. I continue to learn from
Mind Boosters book. It
is the one source that I continually return to when exploring nutritional approaches. My
question concerns Tyrosine. I have recently begun taking Acetyl L-Tyrosine, one 300 mg.
tablet in the morning. It seems to increase energy, and even give a little boost in the
area of verbal fluency (an area that I am very interested in improving). I seem to
"feel like talking" more than I normally would, and the words seem to come a
little more easily. However...I'm having a lot of trouble sleeping, even with this small
(I think) dosage, I seem to have a "wired" feeling. I would hate to give up the
benefits of tyrosine.
A. 300 mg of acetyl-tyrosine is actually, in my opinion, a
high dose. Acetyl-tyrosine is probably much more actice that tyrosine by itself. The
alertness it produces does cause insomnia. A lower dosage may reduce the side effects.
Q. Can tyrosine increase
blood pressure?
A. Yes, tyrosine should be used in only very low dosages by those
with
hypertension.
Q. I have read alot on the site about the cautions of 5-HTP and
would like to ask about whether there are
any risks of using L-Tyrosine in the long-term. For me, this supplement really helps with
my mood but I
would like to know whether the amino acid is safe for daily consumption at a high dose(12
grams). I do not
experiences any side-effects from this amino acid and have not read any reports of toxicty
ever occuring
from its use.
A. Twelve grams of
tyrosine is a very high dose. Side effects could include irritability, anxiety,
heart irregularities and perhaps over the long run could have a pro
oxidant effect on certain brain cells, but this is just my hypothesis. Tyrosine
seems to be more effective in those whose depression is due to low dopamine
levels. It's probably best to not use one particular nutrient to treat
depression for prolonged periods but to alternate different ones such as
St-Johns-Wort, SAMe,
5-HTP, etc.
Q. I searched all over Pubmed. Is there any data
concerning tyrosine and increasing T4 thyroid hormone.
A. We can't find any human research regarding the use of a tyrosine
supplement leading to higher thyroid hormone levels.
Q. I began a supplement program for anxiety and
depression. This program includes L-Tyrosine and other supplements. A couple of
days later I added a GABA supplement. The next morning, approximately 90 minutes
after
taking the GABA supplement my feet, arms, hands and ears began burning, turned
red and swelled slightly. I returned to normal within about an hour. I stopped
the GABA supplement but continued with the L-tyrosine and the other supplements.
Again this morning I experienced the same reaction. Could I be allergic to
L-tyrosine?
A. Tyrosine has side effects that are not related to allergy. An
allergy usually develops as a rash or itching. One simple but not fully
scientific way to tell is to take a small portion of a capsule. If it is an
allergy, the reactions will recur, if the symptoms do not recur, that means it
is most likely a dose dependent side effect of tyrosine.
Q. Does tyrosine enhance
energy
?
A. We don't find
tyrosine to be a good energy enhancer since it tends to cause anxiety and rapid
heart beat.
Q. There are obviously some benefits associated with L-Tyrosine supplementation,
but while researching this supplement, I noticed that it tends to be present in
many breast enhancement supplements for women. I dont see how L-Tyrosine could
enhance breast tissue development, but being a man, I dont want to mess around
with anything that could potentially result in me developing breast tissue (
gynecomastia ). So my question is, is there a risk for a man to get gynecomastia
from supplementing L-Tyrosine?
A. L Tyrosine has cardiac risks of heart palpitations or cardiac
rhythm disturbances, but we are not aware of any issues with breast enhancement.
Q. I have a question about tyrosine. I read that
if you take supplemental tyrosine, you should make sure that it also contains
Phenylalanine or take supplemental Phenylalanine. It also said that
Phenylalanine must be present with Tyrosine in order to produce Tyrosine in the
body. Do you agree? Or is it okay to just take tyrosine alone?
A. Tyrosine and phenylalanine do not need to be taken together,
however some people may like the combination together and for others each
separately works better. There are no hard and fast rules.
Q. When ever I sit down to rest, one or the other lower
leg, starts to twitch every 45 seconds or so. My Doctor without doing any
testing said I have restless leg syndrome and Rx Requip to supposedly replace
the dopamine levels that he believes I am deficient in. The Requip usually, but
not always, stops the twitching within an hours or so and then I can sleep. My
question; have there been any studies to show that taking tyrosine boosts your
bodies ability to produce dopamine, thereby eliminating the deficiency and
potentially the twitch?
A. We have not seen such studies. The use of tyrosine is likely to
increase alertness and interfere with proper sleep.
Q. I found a site which sells a supplement for
sunless tanning. The prescription is L-Tyrosine, (2000 mg per daily dose). Do
you think this is a very bad use for L-Tyrosine?
A. We have not seen any research regarding the use of tyrosine
supplements for sunless tanning. High doses of tyrosine can be dangerous.
Q. I would like to know if ok to take L-tyrosine
and the medication Levothrine.
A. Low amounts may be fine, but high doses of each could cause side
effects including irritability, insomnia, and rapid heart beat.
Mind Boosters: A Guide to
Natural Supplements that Enhance Your Mind, Memory, and Mood
tyrosine benefit for mood and
depression, tyrosine
research benefits of tyrosine for depression and weight loss
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