Nutritional composition of royal jelly
Royal Jelly is a milk like secretion made by worker bees in the hive.
It is so named because it serves as the sole food for the queen bee. It supplies
protein, B-vitamins, vitamins A, C, D, E & K, and more than a dozen key minerals,
along with
amino acids, and other important constituents, including nucleic acids (DNA and
RNA).
Royal jelly and breast cancer
Effect of royal jelly on bisphenol A-induced proliferation of human breast
cancer cells.
Biosci Biotechnol Biochem. 2007 Jan;71(1):253-5. Laboratory of Food
Chemistry, Division of Applied Biological Chemistry, Department of Bioscience
and Biotechnology, Faculty of Agriculture, Kyushu University, Japan.
Royal jelly is known as a functional food containing many useful minerals. In
this study, we found an anti-environmental estrogen activity of royal jelly.
Bisphenol A is an environmental estrogen that stimulates proliferation of human
breast cancer MCF-7 cells. Royal jelly inhibited the growth-promoting effect of
Bisphenol Aon MCF-7 cells, even though it did not affect the proliferation of
cells in the absence of Bisphenol A. In addition, this inhibiting effect of
royal jelly was heat-stable.
Research Update
Royal Jelly prolongs the life span of C3H/HeJ mice:
correlation with reduced DNA damage.
Inoue S, Koya-Miyata S, Ushio S, Iwaki K, Ikeda M, Kurimoto M.
Exp Gerontol. 2003 Sep;38(9):965-9.
Fujisaki Institute, Hayashibara Biochemical Laboratories, Inc, 675-1 Fujisaki,
Okayama 702-8006, Japan.
In this study, we investigate the effect of dietary
royal jelly on tissue
DNA oxidative damage and on the life span of C3H/HeJ mice. In C3H/HeJ mice that
were fed a dietary supplement of RJ for 16 weeks, the levels of
8-hydroxy-2-deoxyguanosine (8-OHdG), a marker of oxidative stress, were
significantly reduced in kidney DNA and serum. Secondly, we determined the
effect of dietary RJ on the life span in C3H/HeJ mice. The 50% mice survivals of
intermediate- (about 6 mg/kg weight) and high-dose groups (about 60 mg/kg
weight) were reached at significantly longer times than that of the control
group according to the generalized Wilcoxon test (p<0.05). The average survival
times were 88 weeks for the control group vs. 79 weeks for the low-dose group
(about 0.6 mg/kg weight), 112 weeks for the intermediate-dose group and 110
weeks for the high-dose group, respectively, showing that RJ extended the
average survival time by about 25% compared to the control group. However, RJ
did not extend the total life span. These results indicated that dietary RJ
increased the average life span of C3H/HeJ mice, possibly through the mechanism
of reduced oxidative damage.
Royal Jelly questions
Q. Thanks for all the clear info on royal jelly. I bought a 7 oz jar of Royal
Jelly that I never opened. It's been kept in the refrigerator for at least 8-9
months and still has the plastic seal around the top. I bought it for internal
use. Is it still OK to take as a supplement? Can I still use it on my skin? How
long can I keep it?
A. You may wish to ask the manufacturer who knows better about the
expiration date of that particular batch.
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