Osteoporosis
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Osteoporosis is a public health problem
affecting 75 million persons in the United States, Europe and Japan, including one third
of postmenopausal women and most of the elderly in the United States, Europe and Japan.
Osteoporosis results in more than 1.3 million fractures annually in the United States.
What is osteoporosis?
Osteoporosis is a condition characterized by deterioration
of bone tissue leading to decreased bone mass and bone fragility.
Osteoporosis treatment
Reduce alcohol
Reduce caffeine
Reduce or stop smoking
Weight bearing exercises
Calcium at mealtime with dinner
calcium supplement is available at
Physician Formulas
web site. You can have a diet with
dairy foods or take extra
calcium
supplements.
Vitamin D is useful in
preventing or treating osteoporosis. Foods rich in vitamin D include milk,
cheese, sardines, cooked greens. Exposure to sun a few minutes a day. Evidence
supports the use of calcium, or calcium in combination with vitamin D
supplementation, in the preventive treatment of osteoporosis in people aged 50
years or older. The ideal dosage of vitamin D and calcium varies with each
individual, but, on average, we suggest a minimum doses of 1000 mg of calcium,
and 600 IU of vitamin D.
Reduce or avoid soft drinks due to their phosphorus content.
Soy isoflavones such as genistein
Dried plums may exert positive effects on bone in postmenopausal women.
Estrogen replacement--use lowest amount of natural estrogens
Selective estrogen-receptor modulators
Diet
and osteoporosis
The Mediterranean diet has food items that contain a complex array of naturally
occurring bioactive molecules with antioxidant, anti-inflammatory and
alkalinizing properties. Therefore, the Mediterranean diet is beneficial in
terms of osteoporosis prevention or treatment.
Osteoporosis prevention
To prevent osteoporosis, try to be physically active, preferably throughout
life. Walk, dance, do pushups, do yoga or stretching for flexibility, reduce
smoking, and, if possible join a gym where you lift weights using all muscle
groups. If you can't join a gym, buy a few cheap barbells and lift weights at
home, do gardening, or lift rocks in your backyard... anything to make your
muscles work. When muscles contract, they pull tendons that are attached to the
bones, and this tells the bones to deposit calcium and thus bones become
stronger and less apt to fracture. Bone is a living tissue that responds to
exercise by becoming stronger. Just as a muscle gets stronger and bigger with
use, a bone becomes stronger and denser when it is called upon to bear weight.
Taking lots of calcium without being physically active is not going to be as
effective. Take preemptive action and reduce your chances of having to rely on
osteoporosis drugs.
Cause of osteoporosis
The major processes
responsible for osteoporosis are poor bone mass acquisition during adolescence and
accelerated bone loss in persons during the sixth decade (the perimenopausal period in
women). Both processes are regulated by genetic and environmental factors. Reduced bone
mass is the result of varying combinations of hormone deficiencies, inadequate nutrition,
decreased physical activity, comorbidity and the effects of medications used to treat
various unrelated medical conditions.
Hormones that cause osteoporosis
Depo-Provera (depot
medroxyprogesterone), a popular birth control injection, seems to promote bone
loss or osteoporosis, and the effects increase over a 2-year period.
Depression as cause of
osteoporosis
Low bone mineral density is more common among women
with major depression.
Osteoporosis medications
There is no proof that any one group of osteoporosis medications works
better than other groups. n December of 2008, the Agency for Healthcare Research
and Quality sponsored a team at the Rand Corporation in California to compare
six drugs in the class known as bisphosphonates. These drugs include alendronate
known generically as (Fosamax); zoledronic acid (Zometa); amidronate (Aredia);
etidronate (Didronel), risedronate (Actonel); and ibandronate (Boniva). The
report also evaluatred at estrogen, a synthetic hormone called calcitonin,
calcium, vitamin D, testosterone, parathyroid hormone and drugs in the selective
estrogen receptor modulators (SERM) class such as raloxifene. There was no proof
that bisphosphonates prevent fractures better than estrogen, calcitonin or
raloxifene.
However, estrogen and raloxifene (Evista) can have serious side effects such as
strokes, blood clots in the lungs or bleeding in the uterus. Not enough evidence
exists to determine how exercise or taking testosterone compares to medications
in preventing osteoporosis-related fractures, the researchers said.
Bisphosphonates and osteoporosis
Bisphosphonates are a class of drugs that inhibit the resorption or breakdown of
bone tissue. Bisphosphanates are used for the prevention and treatment of
osteoporosis, multiple myeloma and other conditions that involve bone fragility.
In the last 10 years, millions of patients have taken biphosphanates for the
prevention of osteoporosis and bone thinning from cancer. Bisphosphantes once
seemed safe, but lately concerns have been raised. Bisphosphante use is now
believed to be associated with osteonecrosis (dead bone) of the jaw.
Osteonecrosis of the jaw is an uncommon complication, but it is estimated that
among the 500,000 American cancer patients who take the drugs because their
disease is affecting their bones, up to 10 percent may develop the problem. Some
dentists are refusing to treat patients taking the drugs, fearful that the
dental work will induce a case of osteonecrosis, and lawyers are lining up to
sue the drugs' makers, saying they failed to give patients adequate warning.
Cancer patients, mostly those with multiple myeloma and breast cancer whose
disease has spread to their bones, generally take one of two bisphosphonates,
Zometa or the older Aredia, intravenously. Osteoporosis patients usually take
bisphosphonates as oral pills, in lower doses that patients with cancer. These
bisphosphanate drugs include Fosamax, Actonel and Boniva.
Osteoporosis emails
Q. I had a hysterectomy at age 24. I am now 35 and have been diagnosed with
osteoporosis. I am having a very hard time trying to find out how much of what I
need to take and what would be most helpful for me at my age. The doctors of
course want me to take medication. Unless absolutely necessary I do not wish to
that. Any guidance that you can give would be most appreciated and helpful.
A. We suggest your doctor read this osteoporosis page and guide
you.
Q. Regarding the osteoporosis treatment product
OsteoPhase. It is supposed to regulate calcium homeostasis. I have osteoporosis
and would not mind the expense if the product is effective. What is your
opinion? OsteoPhase contain Ostea Tealienwhanensis (shell), Astralagus
polysaccharide (root), Coix Lachryma-Jobi (seed), and Angelica Sinensis (root)
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