Osteoporosis
pill minerals alternative therapy herbs
natural supplements
Osteoporosis is a public health problem
affecting 75 million persons in the United States, Europe and Japan, including one third
of postmenopausal women and most of the elderly in the United States, Europe and Japan.
Osteoporosis results in more than 1.3 million fractures annually in the United States.
What is osteoporosis?
Osteoporosis is a condition characterized by deterioration
of bone tissue leading to decreased bone mass and bone fragility.
Diet
and osteoporosis
Nutrition is one of many factors that influence bone mass and fragility
fractures. Supplements are helpful, including vitamin D and calcium. There is
some growing evidence that phytoestrogens and nondigestible oligosaccharides
could play a role in reducing the severity of osteoporosis.
The Mediterranean diet has food items that contain a complex array of naturally
occurring bioactive molecules with antioxidant, anti-inflammatory and
alkalinizing properties. Therefore, the Mediterranean diet is beneficial in
terms of osteoporosis prevention or treatment.
Here are some suggestions on how to reduce your chances of
getting
osteoporosis.
Osteoporosis treatment
Reduce alcohol
Reduce caffeine
Reduce or stop smoking
Weight bearing exercises
Calcium at mealtime with dinner.
You can have a diet with
dairy foods or take extra
calcium
supplements.
Vitamin D is useful in
preventing or treating osteoporosis. Foods rich in vitamin D include milk,
cheese, sardines, cooked greens. Exposure to sun a few minutes a day. Evidence
supports the use of calcium, or calcium in combination with vitamin D
supplementation, in the preventive treatment of osteoporosis in people aged 50
years or older. The ideal dosage of vitamin D and calcium varies with each
individual, but, on average, we suggest a minimum doses of 1000 mg of calcium,
and 600 IU of vitamin D.
Reduce or avoid soft drinks due to their phosphorus content.
Soy isoflavones such as genistein
Dried plums may exert positive effects on bone in postmenopausal women.
Estrogen replacement--use lowest amount of natural estrogens
Selective estrogen-receptor modulators
B vitamins and osteoporosis
treatment
The effect of B-vitamins on biochemical bone turnover markers and bone mineral
density in osteoporotic patients: a 1-year double blind placebo controlled
trial.
Clin Chem Lab Med. 2007; ANZAC Research Institute, University of
Sydney, Sydney NSW, Australia and Department of Clinical Chemistry and
Laboratory Medicine, University Hospital of Saarland, Homburg, Germany.
This study analyzed the effect of a homocysteine lowering treatment in
individuals with osteoporosis. Patients with osteoporosis were treated with
either a combination of 2.5 mg folate, 0.5 mg vitamin B12 and 25 mg vitamin B6
or placebo. B-vitamin supplementation had no consistent effects on bone turnover
or bone mineral density.
Vitamin D and osteoporosis
Vitamin D3 is crucial for optimal bone health. Vitamin D increases intestinal
absorption of calcium and phosphorus. Vitamin D deficiency [as defined by a
serum 25(OH)D level of less than 20 ng/mL] is pandemic. This deficiency is very
prevalent in patients with osteoporosis. Vitamin D deficiency causes osteopenia,
osteoporosis and osteomalacia, increasing the risk of fracture. Unlike
osteoporosis, which is a painless disease, osteomalacia causes aching bone pain
that is often misdiagnosed as fibromyalgia or chronic pain syndrome or is simply
dismissed as depression. Vitamin D deficiency causes muscle weakness, increasing
the risk of falls and fractures, and should be aggressively treated with
pharmacological doses of vitamin D. Vitamin D sufficiency can be sustained by
sensible sun exposure or ingesting at least 800 IU of vitamin D3 daily. Patients
being treated for osteoporosis should be adequately supplemented with calcium
and vitamin D to maximize the benefit of treatment.
Osteoporosis
minerals
In addition to calcium, other minerals that may be helpful for patients with
osteoporosis include magnesium, boron, phosphorus, and strontium. Little long
term research is available with these minerals to know what role they play in
the long term management of osteoporosis prevention or treatment.
Osteoporosis prevention
To prevent osteoporosis, try to be physically active, preferably throughout
life. Walk, dance, do pushups, do yoga or stretching for flexibility, reduce
smoking, and, if possible join a gym where you lift weights using all muscle
groups. If you can't join a gym, buy a few cheap barbells and lift weights at
home, do gardening, or lift rocks in your backyard... anything to make your
muscles work. When muscles contract, they pull tendons that are attached to the
bones, and this tells the bones to deposit calcium and thus bones become
stronger and less apt to fracture. Bone is a living tissue that responds to
exercise by becoming stronger. Just as a muscle gets stronger and bigger with
use, a bone becomes stronger and denser when it is called upon to bear weight.
Taking lots of calcium without being physically active is not going to be as
effective. Take preemptive action and reduce your chances of having to rely on
osteoporosis drugs.
Cause of osteoporosis
The major processes
responsible for osteoporosis are poor bone mass acquisition during adolescence and
accelerated bone loss in persons during the sixth decade (the perimenopausal period in
women). Both processes are regulated by genetic and environmental factors. Reduced bone
mass is the result of varying combinations of hormone deficiencies, inadequate nutrition,
decreased physical activity, comorbidity and the effects of medications used to treat
various unrelated medical conditions.
Antidepressants and
osteoporosis
People aged 50 and older who take SSRI antidepressants, including Zoloft,
Prozac and other top-sellers, have a higher risk of osteoporosis and broken
bones compared with those who don't use the SSRI drugs. Antidepressants have
been linked with low blood pressure and dizziness leading to falls, which can
increase risks for broken bones. Research in animals suggests that SSRI drugs
have a direct effect on bone cells, decreasing bone strength and size.
Hormones that cause osteoporosis
Depo-Provera (depot
medroxyprogesterone), a popular birth control injection, seems to promote bone
loss or osteoporosis, and the effects increase over a 2-year period.
Depression and osteoporosis
Low bone mineral density is more prevalent in premenopausal women with
depression. The bone mineral density deficits are of clinical significance and
comparable in magnitude to those resulting from established risk factors for
osteoporosis, such as smoking and reduced calcium intake. Immune or inflammatory
imbalance may cause low bone mineral density in premenopausal women with
depression. However, it is possible that lack of exercise due to depression may
be a contributing factor to osteoporosis in women with depression.
Osteoporosis medications
There is no proof that any one group of osteoporosis medications works
better than other groups. n December of 2008, the Agency for Healthcare Research
and Quality sponsored a team at the Rand Corporation in California to compare
six drugs in the class known as bisphosphonates. These drugs include alendronate
known generically as (Fosamax); zoledronic acid (Zometa); amidronate (Aredia);
etidronate (Didronel), risedronate (Actonel); and ibandronate (Boniva). The
report also evaluatred at estrogen, a synthetic hormone called calcitonin,
calcium, vitamin D, testosterone, parathyroid hormone and drugs in the selective
estrogen receptor modulators (SERM) class such as raloxifene. There was no proof
that bisphosphonates prevent fractures better than estrogen, calcitonin or
raloxifene.
However, estrogen and raloxifene (Evista) can have serious side effects such as
strokes, blood clots in the lungs or bleeding in the uterus. Not enough evidence
exists to determine how exercise or taking testosterone compares to medications
in preventing osteoporosis-related fractures, the researchers said.
Emails
Q. I had a hysterectomy at age 24. I am now 35 and have been diagnosed with
osteoporosis. I am having a very hard time trying to find out how much of what I
need to take and what would be most helpful for me at my age. The doctors of
course want me to take medication. Unless absolutely necessary I do not wish to
that. Any guidance that you can give would be most appreciated and helpful.
A. We suggest your doctor read this osteoporosis page and guide
you.
Q. Regarding the osteoporosis treatment product OsteoPhase. It is supposed to regulate calcium homeostasis. I have osteoporosis and would not mind the expense if the product is effective. What is your opinion? OsteoPhase contain Ostea Tealienwhanensis (shell), Astralagus polysaccharide (root), Coix Lachryma-Jobi (seed), and Angelica Sinensis (root).
Q. Is there anything that can be done regarding bisphosphonate-induced
osteonecrosis of the jaw?
A. See ozone
therapy.
Q. I am fighting
osteoporosis and would
like to take inulin to enhance my calcium & magnesium absorption. I read that
different inulin fructans have different efficacy. So, what form of inulin
should I seek? Is fructooligosaccharide inulin the best?
A. We have seen no long term studies that have evaluated the use of
inulin for osteoporosis. Even after years and decades of research, there is
still no firm agreement in the medical profession regarding the ideal dosages of
calcium, vitamin D, mangesium, or other supplements. Hence the role of inulin in
osteoporosis is likely to be unanswered for quite a while.
Q. Does
coral calcium help
with osteoporosis?
A. It may, but we have not seen any human studies with coral
calcium to know for sure. If the calcium amount is high enough, it should help
with osteoporosis.
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