Multiple Sclerosis
therapy, natural treatment with herbs vitamins
ginkgo fish oil
Nerve fibers inside and outside the brain are wrapped with many layers of
insulation called the myelin sheath. Much like the insulation around an electrical wire,
the myelin sheath permits electrical impulses to be conducted along the nerve fiber with
speed and accuracy. When myelin is damaged, nerves don't conduct impulses properly.
Multiple sclerosis is a disorder in which the nerves of the eye, brain, and spinal cord
lose patches of myelin.
Define multiple
sclerosis
The term multiple sclerosis comes from the multiple areas
of scarring (sclerosis) that represent many patches of demyelination in the nervous
system. The possible neurologic signs and symptoms of multiple sclerosis are so diverse
that doctors may miss the diagnosis when the first symptoms appear. While the disease
often worsens slowly over time, affected people usually have periods of relatively good
health (remissions) alternating with debilitating flare-ups (exacerbations). About 400,000
Americans, mostly young adults, have the disease.
Alternative and
natural therapy for multiple sclerosis
At this point it is very difficult to know with any
certainty which supplements, in what dosages, and in what combination (s) would
be helpful for multiple sclerosis, if at all. We also have little idea how these
supplements interact with medicines currently used for multiple sclerosis. If
you have multiple sclerosis, make your doctor aware of some of these preliminary
studies, and perhaps he or she would want to monitor you while you give them a
try. There is no definite proof yet that these supplements will help. Much more
research is needed before natural options are considered. It is possible that
someone's condition may get worse by stopping their existing medicines and using
natural supplements exclusively. It is also possible that certain natural
supplements may lead to a slight reduction of the necessary pharmaceutical
medication dosage. If you do plan to use these supplements, keep the dosages low
at first until you have a grasp on how they are influencing your condition or
whether they are interfering or improving the actions of the pharmaceutical
medicines.
Fish Oil capsules
could be helpful
Carnitine has been found
helpful in reducing fatigue in patients with multiple sclerosis.
Curcumin may block
the progression of multiple sclerosis.
Ginkgo biloba have shown
intriguing preliminary evidence of efficacy.
Beta sitosterol
Vitamin D may be helpful
Beta sitosterol
and multiple sclerosis
Comparison of the immunomodulatory effects of the plant sterol beta-sitosterol
to simvastatin in peripheral blood cells from multiple sclerosis patients.
Int Immunopharmacol. 2009 Jan; Desai F, Ramanathan M, Fink CS, Wilding
GE, Weinstock-Guttman B, Awad AB. Department of Exercise and Nutrition Sciences,
State University of New York, Buffalo, NY 14214, USA.
Statins as hypocholesterolimic drugs have recently shown to have
ant-inflammatory properties and thus are being assessed for the treatment of
multiple sclerosis. Dietary phytosterols such as beta-sitosterol are also
hypocholesterolemic compounds and from preliminary studies they appear to have
also anti-inflammatory properties. In this communication, we report on studies
to investigate the immunomodulatory effects of beta-sitosterolon proliferation
and release of key cytokines from peripheral blood mononuclear cells (PBMC) of
MS patients. In PBMC of multiple sclerosis patients, 16 microM beta-sitosterol
had no effect on cell proliferation; however simvastatin (SV) at 10 and 20
microM reduced cell proliferation by as much as 60%. beta-sitosterol (4 microM)
reduced TNF-alpha release by 24% in PBMC of MS patients whereas 10 microM SV
reduced TNF-alpha release by 94%. beta-sitosterol reduced IL-12 release in
multiple sclerosis patients at 4 and 16 microM by 27% and 30%, respectively. In
healthy subjects, 16 microM beta-sitosterol increased the anti-inflammatory
cytokine IL-10 by 47% whereas 10 microM SV decreased IL-10 by 30%. In PBMC of
multiple sclerosis patients, beta-sitosterol had no effect on IL-10 release
whereas 10 microM SV reduced IL-10 by 62%. beta-sitosterol (4 microM) reduced
IL-5 release by 47% in MS patients while 10 microM SV reduced IL-5 by 89%. The
results show that beta-sitosterol is effective in modulating the secretion of
pro/anti-inflammatory cytokines and suggest a potential beneficial effect of
beta-sitosterol in multiple sclerosis management without the side effects
associated with statin therapy.
Fatty acids and
multiple sclerosis
Polyunsaturated fatty acids in the pathogenesis and treatment of multiple
sclerosis.
Br J Nutr. 2007 Oct. Harbige LS, Sharief MK. Centre for Bioscience
Research, School of Science, University of Greenwich at Medway, United Kingdom.
In a randomised double-blind, placebo controlled trial of a high dose and low
dose selected GLA (18:3n-6)-rich oil and placebo control, the high dose had a
marked clinical effect in relapsing-remitting multiple sclerosis, significantly
decreasing the relapse rate and the progression of disease. Laboratory findings
paralleled clinical changes in the placebo group in that production of
mononuclear cell pro-inflammatory cytokines (TNF-alpha, IL-1beta) was increased
and anti-inflammatory TGF-beta markedly decreased with loss of membrane n-6
fatty acids linoleic (18:2n-6) and arachidonic acids (20:4n-6). In contrast
there were no such changes in the high dose group. The improvement in disability
in the high dose suggests there maybe a beneficial effect on neuronal lipids and
neural function in multiple sclerosis. Thus disturbed n-6 fatty acid metabolism
in multiple sclerosis gives rise to loss of membrane long chain n-6 fatty acids
and loss of the anti-inflammatory regulatory cytokine TGF-beta, particularly
during the relapse phase, as well as loss of these important neural fatty acids
for CNS structure and function and consequent long term neurological deficit in
multiple sclerosis.
Comments: Future research will indicate which types of fatty acids
are most helpful as a treatment for multiple sclerosis.
Vitamin D and
multiple sclerosis
An abundance of vitamin D seems to help prevent multiple sclerosis. Research
with 7 million people found that white members of the U.S. military with the
highest blood levels of vitamin D were less likely to develop multiple sclerosis
than people with low levels. Multiple sclerosis historically has been more
common in people who live in regions farther from the equator where there is
less intense year-round sunlight. These findings don’t prove that a lack of
vitamin D can cause multiple slerosis, so it’s too preliminary to recommend that
people take vitamin D pills to avoid the disease.
Possible triggers for Multiple Sclerosis
On-the-job exposure to organic solvents may increase a person's risk of
developing MS.
Infection with a common bacteria known as C. pneumoniae
may increase the risk of developing multiple sclerosis.
Multiple
Sclerosis Medical therapy
Injectable beta-interferon, a relatively new treatment, reduces the frequency of
relapses. Other promising treatments still under investigation include other interferons,
oral myelin, and glatiramer to help keep the body from attacking its own myelin. The
benefits of plasmapheresis and intravenous gamma globulins haven't been established, and
these treatments aren't practical for long-term therapy.
Corticosteroids such as prednisone taken by mouth or methylprednisolone
given intravenously for short periods to relieve acute symptoms have been the main form of
therapy for decades.
Psychological
factors in multiple sclerosis
Several psychological disorders occur in patients with
multiple sclerosis.
Depression is the predominant psychological disturbance with lifetime prevalence
around 50 percent. Depression is more common during relapses and it may
exacerbate fatigue and cognitive dysfunction. Anxiety is also frequent, occurs
in newly diagnosed patients, and its co-morbidity with depression has been
suggested to increase the rate of suicidal ideation. In some cases severe stress
may trigger multiple sclerosis symptoms.
Lamotrigine for
multiple sclerosis pain
Approximately 30% of patients with
multiple sclerosis
have central pain. The anticonvulsant lamotrigine is not helpful in reducing
pain in multiple sclerosis patients.
Symptoms
Multiple sclerosis symptoms vary but can be disabling and can include tingling
pain in the arms and legs, fatigue and vision problems.
Incidence of
Multiple sclerosis
Multiple sclerosis is among the most
common nerve disorders affecting young adults, mostly women. About 350,000
people in the United States and 2 million worldwide have MS, a chronic
autoimmune disease in which the body attacks the fatty insulation that surrounds
nerve fibers.
Nerve fibers inside and outside the brain are wrapped with many layers of
insulation called the myelin sheath. Much like the insulation around an electrical wire,
the myelin sheath permits electrical impulses to be conducted along the nerve fiber with
speed and accuracy. When myelin is damaged, nerves don't conduct impulses properly.
Multiple sclerosis is a disorder in which the nerves of the eye, brain, and spinal cord
lose patches of myelin. The term multiple sclerosis comes from the multiple areas
of scarring (sclerosis) that represent many patches of demyelination in the nervous
system. The possible neurologic signs and symptoms of multiple sclerosis are so diverse
that doctors may miss the diagnosis when the first symptoms appear. While the disease
often worsens slowly over time, affected people usually have periods of relatively good
health (remissions) alternating with debilitating flare-ups (exacerbations). About 400,000
Americans, mostly young adults, have the disease.
Questions
Q. Finally. some hope. Just came off Copaxone for
multiple sclerosis.
Need any info on natural methods for treatment.
A. We will update this page regarding natural treatment for
multiple sclerosis.
Q. When my twins were five months old, I was diagnosed with multiple sclerosis.
As much as it was a shock to myself and my family, I had to deal with this
reality and since April 2006, I have been injecting myself with Copaxone every
night since then. Copaxone, manufactured by Teva Marion Partners, is the brand
name for a synthetic chemical used to modify the course of multiple sclerosis.
Recently, within the last two weeks, I have had a slight relapse where I was
semi dizzy and have had to stay home, no driving. I called my neurologist, told
him of my relapse and he suggested I might take three shots of a steroid. I have
not done that yet because, well, when I was diagnosed with this disease, my Mom
and Dad did lots of research on line and found two homeopathic methods to
possibly reverse these symptoms. One of these homeopathic methods is Riso Triene
and Mona Vie. RiSotriene is a concentrated stabilized rice bran. Mona Vie is
acai. When I became dizzy again, I began drinking Riso Triene at least three
times a day and when my mom got a shipment of Mona Vie out to me, I also began
drinking that twice a day. It usually takes a month, as you know, for any new
product you are consuming to work with your body. So, I have only began drinking
Mona Vie for a couple of weeks. As of right now, I am beginning to feel better.
A little dizzy still and not driving. I will not drive again until I am
completely better. Oh, and the Riso Triene, that in the beginning was difficult
to try and drink everyday because my twins are always at my feet and legs and
make it hard for me to practically do anything. But, I have had no choice to
drink this now that my health was failing me again. With that said, can you
please give me some advise on what supplements would be real good for me to take
along with these products I am already taking?
My neurologist knows I am taking these and he also suggested I look for other
supplements that may be of help to me.
A. We wish you well, and perhaps some of the supplements mentioned
on this page could help you.
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