LongJack product
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Tongkat Ali (Eurycoma longifolia jack, also promoted as Longjack) is a small tree found in the jungles throughout Malaysia and Southeat Asia. It is commonly known as Tongkat Ali in Malaysia and Singapore, Piak or Tung Saw in Thailand, and Pasak Bumi in Indonesia.

Tongkat Ali Longjack, 400 mg - Longjack powder by Physician Formulas
Tongkat Ali, also known as Longjack, grows wild in the rainforests of the Southeast Asia. In Indo-China. In Malaysia, Longjack is known for its energy, tonic, and sensual vitality properties. Longjack: Traditionally used to improve energy, reduce fatigue and enhance overall physical and sensual performance. This longjack product is of the pure quality raw material directly from Malaysia.

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How is longjack sold in Asia?
In the old days, the longjack roots had to be brewed for long hours to get a bitter extract. Now Tongkat Ali, which literally means Ali's cane, is conveniently packed in pill or "tea-bag" form and mixed with regular coffee or tea. Tongkat Ali coffee and tea are now sold in Malaysia's ubiquitous roadside hawker stalls, supermarkets and even at eateries in posh hotels.

What the Research Says about Longjack:
Aphrodisiac benefit - Over the past few years, there have been quite a number of studies that have shown longjack to have sex-boosting properties. The effects of longjack were studied on the libido of male rats after dosing them with up to 800 mg per kilogram of body weight twice daily for 10 days. Results showed that longjack produced a dose-dependent increase in mounting frequency, that is, the number of times the male rats tried to mount the female rats increased as the dose given to the rats increased. In addition, the rats displayed more frequent and vigorous licking and anogenital sniffing towards the receptive females. Furthermore, the rats dosed with longjackspent more time grooming their genitals compared to the rats who were not given the plant. Genital grooming may be interpreted as masturbation. The researchers noticed another interesting finding: while the rats who had not received the plant showed normal behavior within the cage such as exploration and climbing the cage wall, the rats given longjack stayed around the females instead of exploring the cage. Longjack also increased the frequency of the rats' erections. For more information on erection enhancer herbs. For more information on aphrodisiac natural herbs.

Longjack and Cancer treatment
Beta-carboline alkaloids isolated from longjack, have demonstrated significant cytotoxicity against human lung cancer (A-549) and human breast cancer (MCF-7) cell lines.

Longjack and Malaria
Interestingly, scientists have found that, in addition to its sex-enhancing effects, compounds within longjack have anti-malarial properties.

Longjack mechanism of action
Very little is known regarding the mechanisms of action of longjack. Recent studies indicate that the root contains several compounds including beta-carboline alkaloids and quassinoid-type glycosides. How these compounds and many others in Tongkat Ali influence the human sexual response is not clearly understood at this time. I have read promotional material by some vitamin companies regarding longjack that it enhances testosterone production, however I have not been able to definitively confirm this claim through a Medline search.

The herbs in Passion Rx include Ashwagandha, Catuaba, Cnidium, Muira Puama, Tribulus, Tongkat ali, and Yohimbe. Another herb found in Passion Rx is horny goat weed.

Longjack Availability
Tongkat ali is sold as a powder, and in capsules, sometimes mixed with other herbs. There are a number of extracts available in various potencies, and since each company will have a different way of extracting, it is difficult to give dosages that would be consistently effective.

Longjack side effects
High doses of longjack cause insomnia and increased body temperature, along with quicker heart beat and even arrhythmias on very high dosages. Another side effect is restlessness or easy to anger. Long term side effects are not fully understood.

Longjack Research Update
Eurycoma longifolia Jack enhances sexual motivation in middle-aged male mice.
J Basic Clin Physiol Pharmacol. 2003;14(3):301-8. Ang HH, Lee KL, Kiyoshi M. School of Pharmaceutical Sciences, University Science Malaysia, Minden, Penang, Malaysia.
Longjack  was investigated for sexual motivation activity in adult, middle-aged male mice and in retired breeders, using the modified open field and the modified runway choice methods. Each mouse received 500 mg/kg of one of 4 fractions of Longjack, viz. chloroform, methanol, butanol, and water, whereas the mice in the control and yohimbine groups received 3 ml/kg of normal saline and 30 mg/kg of yohimbine daily respectively for 10 d. The results show a transient increase in the percentage of male mice responding to the right choice after chronic consumption of the fractions with 50 percent of the adult middle-aged male mice treated with Longjack  and yohimbine scoring the right choice after 8 and 5 days post-treatment respectively. In conclusion, this study has shown that Longjack continues to enhance sexual motivation in adult, middle-aged male mice and in retired breeders.

Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia.
Kuo PC, Damu AG, Lee KH, Wu TS.
Department of Chemistry, National Cheng Kung University, Tainan 701, Taiwan, ROC.
Bioorg Med Chem. 2004 Feb 1;12(3):537-44.
Sixty-five compounds were isolated from the roots of Longjack. Among these isolates, four quassinoid diterpenoids were reported from natural sources for the first time, namely eurycomalide A, eurycomalide B (2), 13beta, 21-dihydroxyeurycomanol (3), and 5alpha, 14beta, 15beta-trihydroxyklaineanone (4). Compounds 12, 13, 17, 18, 36, 38, 59, and 62 demonstrated strong cytotoxicity toward human lung cancer (A-549) cell lines, however, 12, 13, 17, 38, 57, 58, and 59 exhibited strong cytoxicity toward human breast cancer (MCF-7) cell lines. Compounds 57 and 58 displayed potent antimalarial activity against the resistant Plasmodium falciparum. The thorough studies on the stereochemistry of the different quassinoid diterpenoids provide a clear reference to the scientists who are interested on this field.

Effect of Eurycoma longifolia Jack on libido in middle-aged male rats.
Ang HH, Lee KL.
School of Pharmaceutical Sciences, University Science Malaysia, Minden, Penang, Malaysia.
J Basic Clin Physiol Pharmacol. 2002;13(3):249-54.
The effect of increasing doses of various fractions of longjack extracts on libido was examined in middle-aged male rats. The results showed that a high dose (800 mg/kg) of all Longjack extracts significantly increased mount frequency over that of untreated controls, but had no effect on the frequency of intromission or ejaculation. The results of this study show that Longjack extracts can increase libido in middle-aged male rats.

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