Feverfew grows widely across Europe and North America. The leaves of feverfew have been historically used for the therapy of fever and more recently migraine headaches. For centuries, healers relied on the feathery green leaves of feverfew (Tanacetum parthenium) to treat headaches, stomach upset, rheumatoid arthritis, and menstrual problems. The bright yellow and white blossoms of this flower, which grows wild throughout Europe and South America, emit a powerful aroma that was once thought to purify the air and prevent disease. Feverfew has also long been used in gardens to repel bees and various insects. And as its common name suggests, it was once popular for reducing fever. The herb was somewhat forgotten, however, until the late 1970s. That's when migraine sufferers started talking about feverfew's potential to ward off these often debilitating headaches. For more feverfew information.

Feverfew extract, 30 Capsules - Enzymatic Therapy
Feverfew  (Tanacetum parthenium) is stabilized and standardized to guarantee 600 mcg of Parthenolide per capsule (verified by HPLC).  Parthenolide is feverfew's most beneficial compound.  Feverfew is made from feverfew flowers and leaves harvested when the plant is richest in Parthenolide content.  Just one capsule daily provides the maximum value feverfew has to offer.

Recommendations: One to three feverfew extract capsules daily. Best results are obtained with consistent use.

Supplement Facts:
Feverfew - 100 mg
(Tanacetum parthenium) Flower and leaf standardized to contain 600 mcg of parthenolide

Purchase Feverfew extract bottle

What's in Feverfew?
Feverfew herb contains a range of compounds known as sesquiterpene lactones. Over 85% of these are a compound called parthenolide. The active ingredient in feverfew, parthenolide, specifically binds to and inhibits a protein which plays a role in the body's inflammatory process. Fever is part of the body's inflammatory response, and inflammation contributes to a range of ailments--including migraines. Parthenolide helps prevent excessive clumping of platelets and inhibits the release of certain inflammatory chemicals. Feverfew's active ingredient parthenolide specifically binds to and inhibits the protein IKK-beta, which plays a role in the body's inflammatory process. Fever is part of the body's inflammatory response, and inflammation contributes to a range of ailments--including migraines.
   The routine dosage of feverfew is 100 to 300 mg up to four times a day, 0.2 to 0.4% parthenolide.
   Results of studies with feverfew in the therapy or prevention of migraine headaches have not been consistent.

Feverfew side effects
Since feverfew extract may potentially thin the blood, caution should be taken if you are on coumadin, aspirin, or blood thinners. No major feverfew side effects have been reported in the medical literature as of January 2008.

Enzymatic Therapy - Feverfewextract , 30 Capsules
Feverfew extract is stabilized and standardized to guarantee 600 mcg of Parthenolide per capsule (verified by HPLC).  Parthenolide is feverfew's most beneficial compound.  Feverfew is made from feverfew flowers and leaves harvested when the plant is richest in Parthenolide content.  Just one capsule daily provides the maximum value feverfew has to offer.
Feverfew (Tanacetum parthenium) Flower and leaf standardized to contain 600 mcg of parthenolide

Feverfew extract summary
Feverfew extract is helpful to some migraine headache sufferers although a review of published studies does not support the view that feverfew is consistently effective.
   The dosage is about 100 to 150 mg of the freeze-dried powdered herb, containing at least 0.4% parthenolide, taken twice a day. Benefits may be noticed within a month or two. Exercise, B vitamins, and magnesium supplements may also help. Some migraine sufferers also notice benefits from a low gluten diet.

Feverfew extract study
Cochrane Database Syst Rev. 2004;(1):CD002286. Department of Complementary Medicine, Peninsula Medical School, Universities of Exeter and Plymouth, 25 Victoria Park Road, Exeter, Devon, UK
Feverfew (Tanacetum parthenium L.) extract is a herbal remedy used for preventing attacks of migraine. To systematically review the evidence from double-blind randomised controlled trials assessing the clinical efficacy and safety of feverfew versus placebo for preventing migraine. Trials using clinical outcome measures were included. Trials focusing exclusively on physiological parameters were excluded. There were no restrictions regarding the language of publication. Data on patients, interventions, methods, outcome measures, results and adverse events were extracted systematically.  Two reviewers independently selected studies, assessed methodological quality and extracted data. Disagreements concerning evaluation of individual trials were resolved through discussion. MAIN RESULTS: Five trials (343 patients) met the inclusion criteria. Results from these trials were mixed and did not convincingly establish that feverfew is efficacious for preventing migraine. Only mild and transient adverse events were reported in the included trials. There is insufficient evidence from randomised, double-blind trials to suggest an effect of feverfew over and above placebo for preventing migraine. It appears from the data reviewed that feverfew presents no major safety problems.

Feverfew extract questions
Q. My 20 year old daughter has Lupus. She has arthritis, severe migraines, she has stage three kidney disease and in 2006 she had a stroke. We cannot get her severe migraines under control. A friend said feverfew may help her headaches. I wanted to know if feverfew will harm her kidney. She also takes a 81 mg aspirin a day. I also need to know if there will be adverse effects due to the aspirin as to thinning her blood too much.
   A. Extracts of the herb feverfew inhibit human blood platelet aggregation thus may thin the blood. We have not seen studies that have combined feverfew with aspirin and therefore we don't know if the addition of feverfew extract to aspirin use will further thin the blood. We are not aware of studies that regarding the role of feverfew extract in terms of kidney health. As far as we know, no kidney damage has been reported in the medical literature with the use of feverfew, however long term studies are not available.

Would taking tribulus herb interact with feverfew extract pill?
    We don't know.