DMAE bitartrate benefits
Does DMAE
help with memory ?
DMAE bitartrate
- Developed by
Dr. Ray Sahelian, M.D.

Suggested use: Take half or one DMAE capsule
in the morning with breakfast.
Click here to buy DMAE
DMAE studies
Studies with DMAE go back to the 1950s. One double blind, placebo-controlled
trial performed in twenty-seven patients with severe Alzheimer's disease did not show
significant benefits (Fisman 1981). Another study on twenty-one patients with memory
deficits was also discouraging since no improvement was found in memory (Caffarra 1980).
However, DMAE was found helpful in patients with age related mental decline. DMAE was
given in a dosage of 600 mg a day for four weeks to fourteen older patients (Ferris 1977).
Ten patients improved and four were unchanged. The patients on DMAE had reduced
depression, less anxiety, and increased motivation, but they had no improvement in memory.
The researchers say, "the results thus suggest that although DMAE may not improve
memory, it may produce positive behavioral changes in some senile patients." Dementia
is a term that is now substituted for senility and is sometimes used to denote a severe
case of age related cognitive decline.
DMAE has been touted as an anti-aging nutrient
but there is no definite proof yet that oral intake of DMAE slows aging
DMAE benefits
Most people notice being more alert and focused within a couple of hours after
taking DMAE. The effects can last most of the day. A few report a higher sense
of wellbeing. DMAE is recommended to be taken in the early part of
the day.
DMAE side effects
DMAE is available in dosages ranging from 100 to 400 mg. It is best to start with a
low dose, such as 50 to 150 mg since high doses can cause anxiety, restlessness, and
muscle tenseness in the neck and shoulders. DMAE taken late in the day may cause insomnia.
Q. I took two capsules of DMAE supplement twice daily
for 3 days and found these dosages can induce irritability, overstimulation, anxiety, headaches and
stiffness in the jaw, neck, and shoulder.
A. Yes, these are common DMAE side effects.
DMAE Availability
DMAE is usually sold by the name of DMAE bitartrate. A 351 mg pill of DMAE
bitartrate yields 130 mg of actual DMAE. It is also available as liquid. One
product contains 35 mg of DMAE per drop. Most users notice an effect from 60 to
150 mg of actual DMAE.
DMAE and Skin
A study shows
Other mind helping supplements besides DMAE
Alpha-GPC
and
Alpha-Lipoic-100
could help brain tissue.
DMAE benefits Summary
DMAE can be helpful in the elderly who have cognitive decline. This nutrient can
also be taken by an adult of any age who needs to be more focused and alert.
DMAE Studies
DMAE Enhances Mood and Alertness
There are dozens of herbs and
nutrients available in health food stores that influence mental function. One that has been popular for many years is DMAE,
which stands for dimethyl-amino-ethanol. A recent German study evaluated the
brain's electrical reaction during presentation of videoclips of 7 minute
duration in 80 subjects with borderline emotional disturbance. The researchers
recorded the different emotional states by having the subjects watch these film
excerpts. Half of the subjects were then started on a daily dose of DMAE and
the testing was repeated after 6 and 12 weeks. The testing included showing the
videoclips, filling out mood questionnaires, and also evaluating the brain's
electrical reaction through EEGs (electrodes placed on the scalp that measure
brain activity) . The results showed that those who took the DMAE daily had less
of a decrease in theta and alpha1 brain electrical activity indicating that they
were more alert. Furthermore, the questionnaires revealed that those on DMAE had
a better mood. The researchers conclude, "DMAE can be interpreted to induce a
psychophysiological state of better feeling of wellbeing on both levels of
analysis mood and electrical pattern of brain activity in subjects suffering
from borderline emotional disturbance."
Comments: Most people notice being more alert
and focused within a couple of hours after taking DMAE. DMAE is available in
dosages ranging from 100 to 400 mg. It is best to start with a low dose, such as
50 to 150 mg of actual DMAE since high doses can cause anxiety, restlessness, and muscle
tenseness in the neck and shoulders. DMAE taken late in the day may cause
insomnia.
Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral
drug combination on EEG patterns in the presence of different emotional states.
Dimpfel W. Forschung und Entwicklung -,
Kurt-Schumacher-Str. 9, D-35440 Linden, Germany.
Eur J Med Res. 2003 May 30;8(5):183-91.
The psychophysiological model of provoking different emotional states by
watching film excerpts with various emotional contents was used to characterize
drug action in 80 subjects (male/female=50%) with threshold emotional
disturbance within a randomized, group-parallel, double-blind,
placebo-controlled study. Analyzing the brain's electrical reaction during
presentation of 5 videoclips of 7 min duration followed by 3 minutes pause
revealed a content specific representation of topographical frequency changes.
This procedure was repeated after 6 and 12 weeks of daily intake of a
vitamin-mineral drug combination containing dimethylaminoethanol (DMAE) or placebo. Subjects taking the active drug for 3 months developed
significant less theta and alpha1 power in sensomotoric areas of the cortex. The
grade of change and statistical significance was dependend on the content of the
excerpt, but the pattern of changes in general remained the same. Since
decreases in theta and alpha1 electrical power have been associated with
increased vigilance and attention, subjects taking the drug combination
obviously were more active and felt better. - Analysis of the emotional change
in mood profile as induced by the TV session was achieved by completing two
different quenstionaires (POMS and Bf-S). Both scores revealed a better mood for
the active drug group thus corroborating the results from EEG analysis.
Therefore the vitamin-mineral drug combination containing DMAE can be
interpreted to induce a psychophysiological state of better feeling of wellbeing
on both levels of analysis mood and electrical pattern of brain activity in
subjects suffering from borderline emotional disturbance.
DMAE pill emails
Q. Should DMAE be taken every day?
A. Our personal preference is that DMAE should
not be taken every day. If DMAE gives you positive benefits, you may take a
bread for a couple of days a week and if you really wanted to take another mind
booster, you could try acetyl-l-carntine.
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