Cordyceps supplement

Cordyceps, one of the better-known traditional Chinese medicines, consists of the dried fungus Cordyceps sinensis growing on the larva of the caterpillar. It is commonly used in China for the replenishment of body health. One of the known pharmacological effects is its anti-oxidation activity. See also Reishi.

Full Spectrum Cordyceps 450 mg, 120 Tablets - Planetary Formulas

In China, Cordyceps sinensis is recognized as a premier tonifier. Full Spectrum Cordyceps 450 provides the same amount of cordyceps CS-4 extract (standardized to 0.1% adenosine) used in clinical studies.  This is combined with cordyceps mycelia, grown on organic brown rice form spores originally gathered in the Himalayas. This combination insures a full spectrum of important cordyceps constituents.

Suggested Use:  One cordyceps tablet, 1 to 2 times daily between meals, or as recommended by your health care professional.

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Properties of Cordyceps
Antioxidant
The extracts of cultured cordyceps sinensis possess potent antioxidant and anti-lipid peroxidation activities and inhibit accumulation of cholesteryl ester in macrophages via suppression of LDL oxidation.

Cordyceps supplement and Diabetes
Cordyceps improves glucose metabolism and increases insulin sensitivity in normal rats.

Energy
A 5 week study using a trademarked formula CordyMax Cs-4 had no effect on aerobic capacity or endurance exercise performance in endurance-trained male cyclists. The dose used was 3 grams a day.

Cordyceps supplement and Hepatitis B
Cordyceps may be helpful in treating hepatitis B. One study showed an improvement in the CD4 to CD8 ratio with the use of cordyceps for 3 months.

Immune system
Cordyceps has an influence on the immune system, although the research is still too early to know the full details.

Cordyceps supplement and leukemia
Cordyceps sinensis mycelium extract induces human premyelocytic leukemia cell apoptosis through mitochondrion pathway.
Exp Biol Med (Maywood). 2007 January. Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
This study was to identify the signaling pathways for the induction of HL-60 cell apoptosis by Cordyceps sinensis mycelium extract. Cordyceps sinensis extract at 25 mug/ml induced nuclear fragmentation and DNA degradation, two hallmark events of apoptosis, Our results suggest that Cordyceps sinensis mycelium extract induces apoptosis in HL-60 cell through the mitochondrial pathway rather than the death receptor pathway.

Q. I was very impressed with your website. I suffer form chronic myelogenous leukemia CML an I am doing well on Imatinib, known by the product name Gleevec. My blood count shows good results with a combination of feverfew, curcumin and black pepper. Recently I learned about cordyceps mushroom and the good influence on leukemia Now I was considering to start using this. According to a Chinese research team in can boost up natural killer cells activity in leukemia patients to 400 percent. According to a Sloan Kettering however cordyceps shows proliferation of progenitor red blood cells and therefore should not be used in myelogeous cancers. Being impressed with your expertise I would be very happy to know your opinion.
   A. It is very difficult to extrapolate from in vitro lab studies to what would occur if a cordyceps supplement was taken orally. Also, the effects may be influenced by the type of cordyceps extract and the dosage used. There won't be easy answers until actual cordyceps studies are done in humans with different types of leukemia. Also, it is difficult to predict the influence of a cordyceps supplement when used in combination with medications and other supplements.

Full Spectrum Cordyceps 450™, 450 mg, 120 Tablets
Planetary Formulas

In China, Cordyceps sinensis is recognized as a premier tonifier . Cordyceps 450 provides the same amount of cordyceps CS-4 extract (standardized to 0.1% adenosine) used in clinical studies.  This is combined with cordyceps mycelia, grown on organic brown rice form spores originally gathered in the Himalayas. This combination insures a full spectrum of important cordyceps constituents.

Cordyceps sinensis Mycelia CS-4 Standardized Extract (0.1% adenosine)
Cordyceps sinensis Mycelia

Does Cordyceps have Aphrodisiac properties?
There are claims that cordyceps is an aphrodisiac. We are not able to find human studies regarding cordycep's influence on sexuality. However a mouse study indicates that cordyceps can stimulate testosterone release.

Lupus
Cordyceps has been studied in systemic lupus erythematosus in rats. Cordyceps sinensis could inhibit lymphadenectasis, reduce the level of proteinuria and anti-ds-DNA antibody in plasma, and improve kidney function in SLE rats.

Sex
There are claims that cordyceps is an aphrodisiac. We are not able to find human studies regarding cordycep's influence on sexuality. However a mouse study indicates that cordyceps can stimulate testosterone release.

Anti-aging effect of Cordyceps extract in mice
Cordyceps, one of the better-known traditional Chinese medicines, consists of the dried fungus cordyceps sinensis growing on the larva of the caterpillar. It is commonly used in China for the replenishment of body health. One of the known pharmacological effects is its anti-oxidation activity. Cordyceps is also known as an immune system stimulant. To investigate the anti-aging effect and mechanism of cordyceps, aged mice were treated with cordyceps extract. After six weeks, the scientists found that cordyceps significantly increased their ability to learn, remember, and it improved the activity of their antioxidant systems.
    There are many herbs, mushrooms, and supplements that have shown similar properties. It's probably a good idea to take cordyceps a few times a month. We generally prefer not to take the same herb or supplement every day and all the time. It's good to take breaks and have variety.

Cordyceps study
In vivo stimulatory effect of Cordyceps sinensis mycelium and its fractions on reproductive functions in male mouse.
Huang YL. National Cheng Kung University, #1, Ta-Hsueh Road, Tainan, Taiwan 70101, ROC.
Life Sci. 2004 Jul 16;75(9):1051-62.
Cordyceps sinensis, an Ascomycetes fungus parasitic to Lepidoptera larvae, has been traditionally used as nutritious food for the enhancement on sexual performance and the restitution of impairment in sexual function in Chinese society. We have previously demonstrated the stimulatory effect of Cordyceps sinensis and its fractions on steroidogenesis both on primary mouse Leydig cells and MA-10 mouse Leydig tumor cells. In the present studies, we determined the in vivo effects of Cordyceps sinensis and its fractions on steroidogenesis in mouse. Different concentrations of CS and Cordyceps sinensis fractions (0.02 and 0.2 mg/g body weight) were fed to immature or mature mice from 1 to 7 days. The plasma levels of testosterone were evaluated by radioimmunoassay. The weights of reproductive organs were also determined. Results illustrated that Cordyceps sinensis significantly induced plasma testosterone levels both in immature and mature mice in 3 and/or 7 days treatment. F2 and F3 at 0.02 and/or 0.2 mg/g body weight for different feeding duration could also significantly stimulated plasma testosterone levels both in immature and mature mice. In general, Cordyceps sinensis, F2 and F3 didn't have considerable effect on the weights of reproductive organs. Taken together, these studies illustrate that Cordyceps sinensis and its fractions significantly stimulated in vivo mouse testosterone production.

Cordyceps supplement emails
Could you please clear my doubts about cordyceps supplement. I have read that it is recommended for SLE. I've read cordyceps is used for replenishment of general body health and has a broad range of actions on the liver, kidneys, heart, and immune system. Isn't there a danger that an herb with such properties could stimulate the immune system? If so, it could cause a great aggravation in SLE (similar ones experienced with astragalus, ginseng, echinacea, zinc, and other immune-stimulating supplements) -- I am speaking from years of painful personal experience. Unfortunately, even substances that are described as having a "BALANCING" action on the immune system (e.g.maritime bark-derived formulas), in fact stimulate it and aggravate an autoimmune disease. So what about cordyceps? Unfortunately, there is not much information. I would be happy to know that it could mimic prednisone, down-regulate the immune system and thus reduce inflammation.
   A. You raise a good point. Any supplement that has a strong influence on the immune system could have effects that are not predictable. Not much is known about the long term use of herbs that stimulate the immune system and whether they have long term side effects. There is also a wide range of response among individuals. As to cordyceps supplements, it is a good idea to take frequent breaks from use.

Q. From the website, you are in the product containing the cordyceps powder. Our company is one of the most earliest and biggest manufacturers specializing in producing cordyceps mycelium powder by liquid-fermentation technology in China. Zhejiang Wanfeng Medicines Group, 51 Renmin Road, Xiaoshan District, Hangzhou City, Zhejiang, Prov., China. Postcode: 311201

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