NOW foods Cat's Claw "5000" - Cats claw is a natural
extract of the highest quality inner bark of authentic Uncaria

tomentosa, an exciting herbal discovery from the Peruvian Rainforest. Also called Una de
Gato, cat's claw herb has been used for hundreds of years by the native Ashanica Indians.
Cat's Claw "5000" is a concentrated water and alcohol extract standardized to contain a minimum of 3% total alkaloids (calculated as mitraphylline) and 15% total Polyphenols.
You can buy Cat's Claw supplement or Joint Power Rx with Cat's Claw extract
High Quality products formulated by a
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Potential uses of Cat's Claw
Anti-inflammatory
Cat's claw is a remarkably potent inhibitor of TNFalpha production. The primary mechanism for cat's claw anti-inflammatory actions
appears to be immunomodulation via suppression of TNFalpha synthesis.
Antioxidant
Cat's claw is an effective antioxidant.
Antitumor
Cat's claw extracts exert a direct anti-proliferative activity
on MCF7 (a breast cancer cell line).
Arthritis
This plant is an effective treatment for osteoarthritis and
probably rheumatoid arthritis (see bottom of page). The species, U guianensis and U tomentosa are equiactive. They are effective antioxidants, but their
anti-inflammatory properties may result from their ability to inhibit TNFalpha and to a
lesser extent PGE2 production.
DNA repair
Human volunteers who took cat's claw for 8 weeks had improved
DNA repair.
Memory
Cat's claw total alkaloids exert a beneficial effect on memory
impairment induced by the dysfunction of cholinergic systems in the brain and that the
effect of the total alkaloids is partly attributed to the oxindole alkaloids tested.
Cat's Claw "5000" is a natural extract of the highest quality inner bark of authentic Uncaria tomentosa, an exciting herbal discovery from the Peruvian Rainforest. Also called Una de Gato, it has been used for hundreds of years by the native Ashanica Indians. Cat's Claw "5000" is a concentrated water and alcohol extract standardized to contain a minimum of 3% total alkaloids (calculated as mitraphylline) and 15% total Polyphenols.
Cat's Claw study
Randomized double blind trial of an extract from the pentacyclic
alkaloid-chemotype of uncaria tomentosa
(Cat's Claw) for the treatment of rheumatoid arthritis.
Mur E. Innsbruck University Hospital, Austria.
J Rheumatol. 2002 Apr;29(4):678-81.
To evaluate safety and clinical efficacy of a plant extract from
the pentacyclic chemotype of Uncaria tomentosa (UT) in patients with active
rheumatoid arthritis (RA). METHODS: Forty patients undergoing sulfasalazine or
hydroxychloroquine treatment were enrolled in a randomized 52 week, 2 phase
study. During the first phase (24 weeks, double blind, placebo controlled),
patients were treated with UT extract or placebo. In the second phase (28 weeks)
all patients received the plant extract. RESULTS: Twenty-four weeks of treatment
with the UT extract resulted in a reduction of the number of painful joints
compared to placebo (by 53.2% vs 24.1%; p = 0.044). Patients receiving the UT
extract only during the second phase experienced a reduction in the number of
painful (p = 0.003) and swollen joints (p = 0.007) and the Ritchie Index compared to the values after 24 weeks of placebo. Only minor side effects
were observed. This small preliminary study demonstrates relative
safety and modest benefit to the tender joint count of a highly purified extract
from the pentacyclic chemotype of cat's claw in patients with active RA taking
sulfasalazine or hydroxychloroquine.
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