Carotenoids capsule
Carotenoids carotene lycopene lutein zeaxanthin cryptoxanthin beta-carotene health benefits

Carotenoids are a group of fat soluble pigments widely distributed in plants and animals. Dietary carotenoids are thought to provide health benefits in decreasing the risk of disease, particularly certain cancers and eye disease. The carotenoids that have been most studied in this regard are beta-carotene, lycopene, lutein, zeaxanthin and astaxanthin. In part, the beneficial effects of carotenoids are thought to be due to their role as antioxidants. Beta-Carotene may have added benefits due its ability to be converted to vitamin A.
   Food sources of these compounds include a variety of fruits and vegetables, although the primary sources of
Lycopene are tomato and tomato products, along with watermelon. Lycopene has been found to reduce the risk of prostate cancer. Egg yolk is a highly bioavailable source of Lutein and zeaxanthin. Lutein and zeaxanthin may be protective in eye disease because they absorb damaging blue light that enters the eye. See lutein eye for more information.
   Carotenoids are available in supplement form. However, intervention trials with large doses of beta-carotene found an adverse effect on the incidence of lung cancer in smokers and workers exposed to asbestos. Until the efficacy and safety of taking supplements containing these nutrients can be determined, current dietary recommendations of diets high in fruits and vegetables are advised. However, it is possible that a combination pill containing several carotenoids may be preferable to taking a high dose of one carotenoid.
   Carotenoids from vegetable juices are able to enhance the immune system in those who normally have a low intake of carotenoids.
   Carotenoids ingested as supplements act as antioxidants, one such carotenoid is
Astaxanthin supplement. You can find carotenoids in Eyesight Rx, a product that helps with vision improvement.

Carotenoid complex 120 capsules - Now Foods

Many diverse carotenoids besides beta-carotene play vital roles in maintaining good health, especially in protecting against free radical damage. Yet, most Americans don't eat enough vegetables.

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Carotenoid study
Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men.

Watzl B. Haid-und-Neu-Strasse 9, DE-76131 Karlsruhe, Germany.
Ann Nutr Metab. 2003;47(6):255-61.
Beta-carotene has been shown to enhance immune functions in humans. Whether vegetables rich in carotenoids, such as beta-carotene or lycopene, modulate immune functions in healthy humans is presently not known. The objective of this study was to investigate the effects of a low-carotenoid diet supplemented with either tomato (providing high amounts of lycopene) or carrot juice (providing high amounts of alpha- and beta-carotene) on immune functions in healthy men. In a blinded, randomized, cross-over study, male subjects on a low-carotenoid diet consumed 330 ml/day of either tomato juice (37.0 mg/day lycopene) or carrot juice (27.1 mg/day beta-carotene and 13.1 mg/day alpha-carotene) for 2 weeks with a 2-week depletion period after juice intervention. Immune status was assessed by measuring lytic activity of natural killer (NK) cells, secretion of cytokines (IL-2, IL-4, TNFalpha), and proliferation by activated peripheral blood mononuclear cells. Juice consumption resulted in relatively fast responses in plasma carotenoid concentrations which were not accompanied by concomitant changes in immune functions. For IL-2, NK cell cytotoxicity, and lymphocyte proliferation, maximum responses were observed during depletion periods. The highest production rate was measured only for TNFalpha at the end of the first intervention period. Juice intervention did not modulate the secretion of IL-4. Increased plasma carotenoid concentrations after vegetable juice consumption are accompanied by a time-delayed modulation of immune functions in healthy men consuming a low-carotenoid diet.

Dietary supplementation with a natural carotenoid mixture decreases oxidative stress.
Kiokias S, Gordon MH. The University of Reading, Whiteknights, Reading, UK.
Eur J Clin Nutr. 2003 Sep;57(9):1135-40.
To determine whether dietary supplementation with a natural carotenoid mixture counteracts the enhancement of oxidative stress induced by consumption of fish oil. DESIGN: A randomised double-blind crossover dietary intervention. Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Whiteknights PO Box 226, Reading RG6 6AP, UK. SA total of 32 free-living healthy nonsmoking volunteers were recruited by posters and e-mails in The University of Reading. One volunteer withdrew during the study. The volunteers consumed a daily supplement comprising capsules containing fish oil (4 x 1 g) or fish oil (4 x 1 g) containing a natural carotenoid mixture (4 x 7.6 mg) for 3 weeks in a randomised crossover design separated by a 12 week washout phase. The carotenoid mixture provided a daily intake of beta-carotene (6.0 mg), alpha-carotene (1.4 mg), lycopene (4.5 mg), bixin (11.7 mg), lutein (4.4 mg) and paprika carotenoids (2.2 mg). Blood and urine samples were collected on days 0 and 21 of each dietary period. The carotenoid mixture reduced the fall in ex vivo oxidative stability of low-density lipoprotein (LDL) induced by the fish oil (P=0.045) and it reduced the extent of DNA damage assessed by the concentration of 8-hydroxy-2'-deoxyguanosine in urine (P=0.005). There was no effect on the oxidative stability of plasma ex vivo assessed by the oxygen radical absorbance capacity test. beta-Carotene, alpha-carotene, lycopene and lutein were increased in the plasma of subjects consuming the carotenoid mixture. Plasma triglyceride levels were reduced significantly more than the reduction for the fish oil control (P=0.035), but total cholesterol, HDL and LDL levels were not significantly changed by the consumption of the carotenoid mixture. Consumption of the natural carotenoid mixture lowered the increase in oxidative stress induced by the fish oil as assessed by ex vivo oxidative stability of LDL and DNA degradation product in urine. The carotenoid mixture also enhanced the plasma triglyceride-lowering effect of the fish oil.

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carotenoids carotene lycopene lutein zeaxanthin cryptoxanthin beta-carotene health benefits