Carnosine benefit as a supplement and the proper dosage, 100 mg 250 mg, 500 mg and 1000 mg
l carnosine side effects and using this supplement for heart health

Carnosine is a small molecule composed of the amino acids histidine and alanine. Carnosine is found in relatively high concentrations in several body tissues—most notably in skeletal muscle, heart muscle, nerve tissue and brain. The exact biological role of carnosine is not well understood, but many studies indicate that carnosine has antioxidant potential. Carnosine may also act as a neurotransmitter (chemical messenger in the nervous system). Carnosine generates nitric oxide better than Arginine. Nitric oxide helps dilate blood vessels. L-Carnosine is a dipeptide composed of the covalently bonded amino acids alanine and histidine and is found in the brain, heart, skin, muscles, kidneys and stomach. L-Carnosine is naturally produced in the body by the enzyme carnosine synthetase. Another nutrient to consider is acetylcysteine, which has its own benefits, particularly as a liver detoxifier.

Buy L Carnosine 500 mg each pill
L-Carnosine is a dipeptide composed of the covalently bonded amino acids alanine and histidine and is found in the brain, heart, skin, muscles, kidneys and stomach. L-Carnosine is naturally produced in the body by the enzyme carnosine synthetase.

L-Carnosine supports healthy aging and cellular rejuvenation by its effects on two mechanisms: Glycosylation and Free Radical Damage. Glycosylation is the oxidation of proteins by glucose resulting in cross-linking of proteins and which is implicated in loss of cell function, genome integrity and accelerated aging. L Carnosine also protects the aging process of the brain by retarding lipid peroxidation and stabilizing cell membranes.

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L Carnosine Supplement Facts
L Carnosine (alanylhistidine) - 500 mg per pill

Carnosine benefit:
Carnosine may be helpful in children with autism. The dose would be much less than in adults.

   From the day she was born, Betty seemed different from other infants. At an age when most infants enjoy interacting with people and exploring their environment, Betty sat motionless in her crib and didn't respond to rattles or other toys. It wasn’t too long before Betty was diagnosed with autism. Unfortunately, modern medicine has little to offer as a cure for this condition. But supplements may be helpful. Researchers at the Autism and Epilepsy Specialty Services in Lake Bluff, Illinois, investigated 31 children with autism in an 8-week, double-blinded study to determine if carnosine would result in changes. Carnosine is a natural substance composed of 2 amino acids. It is found in relatively high concentrations in several body tissues, muscles, and nerve tissue, including the brain. The exact role of carnosine is not well understood, but studies indicate that this nutrient has antioxidant potential and may also act as a neurotransmitter (chemical messenger in the nervous system). The children received 800 mg of carnosine a day and were compared with a group of children on placebo. After 8 weeks, children given carnosine showed statistically significant improvements on several tests including an improvement in vocabulary and recognizing a picture.
     Comments: Carnosine, also known as L-carnosine, is sold in health food stores most commonly in capsules of 500 mg. It would be worthwhile to try 100 to 200 mg of this nutrient before breakfast and lunch for a few weeks under a pediatrician’s supervision.

Carnosine for cataracts
Topical N-Acetyl-carnosine eyedrops shows potential for the treatment and prevention of cataracts.

Babizhayev MA, et al. Efficacy of N-acetylcarnosine in the treatment of cataracts. Drugs R D 2002;3(2):87-103.

L Carnosine helpful in Vegetarians and Diabetic Nephropathy
In recent years l-carnosine has been getting more respect. This nutrient, made of 2 amino acids, alanine and histadine, is gradually getting a reputation as a powerful natural antioxidant. Unfortunately, carnosine is hardly found in a vegetarian diet. Hence, those who don't eat meat products may benefit from taking this nutrient as a supplement. A recent study also points to l carnosine being potentially helpful in diabetic nephropathy (kidney failure) by preventing damage from high sugar levels.
     Most l-carnosine capsules are sold in 500 mg. One option is to take carnosine as a supplement two or three times a week, in the morning. This nutrient has a mild mood balancing effect. Another option is to take half a capsule three or four times a week.


Carnosine as anti-aging supplement
L-Carnosine supports healthy aging and cellular rejuvenation by its effects on two mechanisms: Glycosylation and free radical damage. Glycosylation is the oxidation of proteins by glucose resulting in cross-linking of proteins and which is implicated in loss of cell function, genome integrity and accelerated aging. L-Carnosine also protects the aging process of the brain by retarding lipid peroxidation and stabilizing cell membranes.

Use of carnosine as a natural anti-senescence drug for human beings.
Wang AM, Ma C, Xie ZH, Shen F.Biochemistry (Mosc) 2000 Jul;65(7):869-71. Department of Biochemistry, Harbin Medical University, Harbin 150086, PR China.
Carnosine is an endogenous free-radical scavenger. The latest research indicates that apart from the function of protecting cells from oxidation-induced stress damage, carnosine appears to be able to extend the lifespan of cultured cells, rejuvenate senescent cells, inhibit the toxic effects of amyloid peptide (A beta), malondialdehyde, and hypochlorite to cells, inhibit glycosylation of proteins and protein-DNA and protein-protein cross-linking, and maintain cellular homeostasis. Also, carnosine seems to delay the impairment of eyesight with aging, effectively preventing and treating senile cataract and other age-related diseases. Therefore, carnosine may be applied to human being as a drug against aging.

Side effects
Very high dosages of carnosine can cause nausea and excessive alertness and energy, but, as a rule, few adverse effects are reported on dosage less than 500 mg.

L-Carnosine products
Jarrow Formulas L-Carnosine (alanylhistidine) 500 mg

Carnosine supplement pill questions
I have read the information about carnosine supplement pills on your web site and see where it is composed of the amino acids alanine and histidine. My question is if you are taking a protein supplement which contains these 2 amino acids (L-alanine-563 mg.) and (L-Histidine-574 mg.) per serving would that be comparable to taking the Carnosine supplement?
     When ingesting the two amino acids separately, there is no guarantee that the body will combine them together. They may just be digested and broken down for use as fuel or be incorporated into other peptides or proteins.

My son of three has been diagnosed to be on the autistic spectrum, and will be starting a combination of speech and occupational therapy; as part of a special educational program. We believe he is highly functional as he started recognizing letters and reading words at the age of 2.5. Recently, me and my wife read about carnosine supplement use for autism, and we are eager to try if our son will be benefiting from it. I have the following questions before we proceed with administering carnosine supplements: If he responds to carnosine, will it be a temporary relief for his autistic behavior, or is it a cure? Should we use it in conjunction with his behavioral therapy sessions? Do we need to have his pediatrician oversee its administration, are there any monitoring tests that we need to do to avoid possible adverse effects? How long should he stay on carnosine, and how is the withdrawal process? Any dependencies or drawback effects?
     Very little is known about the use of carnosine supplements in the treatment of children with autism. We suggest that his pediatrician monitor and oversee the use of carnosine. If there is any help for autistic symptoms with the use of carnosine, it is likely to be temporary. Most carnosine pills come in 500 mg and it is best to start with low dosages of about a quarter or a fifth of a capsule. Capsules can be opened by pulling on each end and the contents mixed with water or juice. Long term side effects of the use of carnosine is children is not known, and risks can be minimized by using lower dosages. Research with the use of carnosine supplements in humans is quite limited and there is much that is still not known.

I came upon your site searching for data on carnosin supplements. I'm a shiatsu therapist and lifewave nanno-tech. patches distributor. The company promotes anty aging patches which enhance carnosin production in the body. i have been able to help a patient of mine who claims to expierience a slowing down in the desease"s progression. He is 65 was diagnosed two years ago. I started treating him mainly for welbeeing, with a combination of shiatsu, tweena and physical exersices. Do you have any information on carnosin supplement use and Parkinson's disease?
     Carnosine is a potent antioxidant and may be helpful for Parkinson's disease.

Is there a carnosine study that shows any interactions with herbal pills for sexual enhancement such as tribulus terrestris extract or other such aphrodisiac pills?
     We have not seen such studies. Whenever combining several supplements, it is best to reduce their dosage in order to avoid
carnosine side effects.

I was sent an email by a friend regarding carnosine for longevity enhancement. Is it true that taking this pill can enhance longevity?
     No such studies are available, but this nutrient has many health benefits and perhaps low dosages could someday be found to to have beneficial properties in terms of lifespan.

Dear purchase manager, Shanghai Science Pharmaceutical Chemical Co., Ltd is a specialized manufacturer of amino acid derivatives, peptides, vitamin derivatives and other pharmaceutical and chemical intermediates. Most of our products are exported to worldwide, such as USA, Europe, Japan and India. We are proud of our good service and reputation in this industry. I have learned that you esteemed company supplies the finished product: L-Carnosine for so many years ,one of the ingredients are L-Carnosine, and taking this chance, I would like to introduce you our main product,L-Carnosine(CAS:305-84-0), can prevent diabetic side effects and diabetic complication. It can also act as a new approach to stopping and preventing diabetic retinopathy. Please see the attached specification of L-Carnosine, if you have any queries, please feel free to contact us. If you are interested in any of our products, please feel free to contact us. Yours faithfully, Rosina Fan/ Sales
Shanghai Science Pharmaceutical Chemical Co., Ltd. 859 Chengliu Road, Jiading, Shanghai 201808, China Tel. 86-21-59909001

My name is Rosina Fan, sales of Shanghai Science Pharmaceutical Chemical Co., Ltd is a specialized manufacturer of amino acid derivatives, peptides, vitamin derivatives and other pharmaceutical and chemical intermediates. Most of our products are exported to worldwide, such as USA, Europe, Japan and India. We are proud of our good service and reputation in this industry. I have learned that you esteemed company supplies the finished product: L-Carnosine for so many years ,one of the ingredients are L-Carnosine, and taking this chance, I would like to introduce you our main product,L-Carnosine(CAS:305-84-0), can prevent diabetic side effects and diabetic complication. It can also act as a new approach to stopping and preventing diabetic retinopathy. Please see the attached specification of L-Carnosine, if you have any queries, please feel free to contact us. Rosina Fan / Sales Shanghai Science Pharmaceutical Chemical Co., Ltd. 859 Chengliu Road, Jiading, Shanghai 201808, China